Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand

Background: Acupuncture shows benefits for patients with melasma, although no optimal number of sessions have been determined.Methods: The prospective observational study was conducted in melasma patients who were treated with acupuncture procedures two times a week and were evaluated after the 5th...

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Autores principales:	Thanan Supasiri, Nuntida Salakshna, Krit Pongpirul
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	acupuncture–therapy melasma dose–response melasma area and severity index Thailand Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/0aa4a3766d6c4bed85f1647b50d39688
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spelling	oai:doaj.org-article:0aa4a3766d6c4bed85f1647b50d396882021-11-04T05:09:22ZShort Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand2296-256510.3389/fpubh.2021.761017https://doaj.org/article/0aa4a3766d6c4bed85f1647b50d396882021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpubh.2021.761017/fullhttps://doaj.org/toc/2296-2565Background: Acupuncture shows benefits for patients with melasma, although no optimal number of sessions have been determined.Methods: The prospective observational study was conducted in melasma patients who were treated with acupuncture procedures two times a week and were evaluated after the 5th and the 10th sessions of acupuncture, with a 1-week follow-up after the last session. Participants Groups A and B received five and 10 acupuncture sessions, respectively. Melasma was assessed by using the melanin index (MI), melasma area and severity index (MASI), patient-reported improvement scores, and acupuncture-related adverse events.Results: Out of 113 participants, 67 received five sessions of acupuncture treatment while 39 received 10 sessions. At 1 week after five sessions of acupuncture in Group A, the mean MI decreased by 28.7 (95% CI −38.5 to −18.8, p < 0.001), whereas the median MASI decreased by 3.4 (95% CI −6.9 to −1.2, p < 0.001) points. At 1 week after ten sessions of acupuncture in Group B, the mean MI decreased by 31.3 (95% CI −45 to −17.6, p < 0.001), whereas the median MASI decreased by 5.4 (95%CI −9.9 to −3, p < 0.001) points. The first five sessions of acupuncture had a higher incremental effect than the last five sessions, although there was no statistically significant difference. Twenty-nine participants reported minor side effects. Group B had a risk ratio (RR) of having adverse events 1.8 times (95% CI 1.0–3.4, p = 0.05) compared with Group A.Conclusion: Short acupuncture regimens of 5–10 sessions in melasma seem to be effective and practical with minor side effects.Thanan SupasiriNuntida SalakshnaNuntida SalakshnaKrit PongpirulKrit PongpirulFrontiers Media S.A.articleacupuncture–therapymelasmadose–responsemelasma area and severity indexThailandPublic aspects of medicineRA1-1270ENFrontiers in Public Health, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acupuncture–therapy melasma dose–response melasma area and severity index Thailand Public aspects of medicine RA1-1270
spellingShingle	acupuncture–therapy melasma dose–response melasma area and severity index Thailand Public aspects of medicine RA1-1270 Thanan Supasiri Nuntida Salakshna Nuntida Salakshna Krit Pongpirul Krit Pongpirul Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
description	Background: Acupuncture shows benefits for patients with melasma, although no optimal number of sessions have been determined.Methods: The prospective observational study was conducted in melasma patients who were treated with acupuncture procedures two times a week and were evaluated after the 5th and the 10th sessions of acupuncture, with a 1-week follow-up after the last session. Participants Groups A and B received five and 10 acupuncture sessions, respectively. Melasma was assessed by using the melanin index (MI), melasma area and severity index (MASI), patient-reported improvement scores, and acupuncture-related adverse events.Results: Out of 113 participants, 67 received five sessions of acupuncture treatment while 39 received 10 sessions. At 1 week after five sessions of acupuncture in Group A, the mean MI decreased by 28.7 (95% CI −38.5 to −18.8, p < 0.001), whereas the median MASI decreased by 3.4 (95% CI −6.9 to −1.2, p < 0.001) points. At 1 week after ten sessions of acupuncture in Group B, the mean MI decreased by 31.3 (95% CI −45 to −17.6, p < 0.001), whereas the median MASI decreased by 5.4 (95%CI −9.9 to −3, p < 0.001) points. The first five sessions of acupuncture had a higher incremental effect than the last five sessions, although there was no statistically significant difference. Twenty-nine participants reported minor side effects. Group B had a risk ratio (RR) of having adverse events 1.8 times (95% CI 1.0–3.4, p = 0.05) compared with Group A.Conclusion: Short acupuncture regimens of 5–10 sessions in melasma seem to be effective and practical with minor side effects.
format	article
author	Thanan Supasiri Nuntida Salakshna Nuntida Salakshna Krit Pongpirul Krit Pongpirul
author_facet	Thanan Supasiri Nuntida Salakshna Nuntida Salakshna Krit Pongpirul Krit Pongpirul
author_sort	Thanan Supasiri
title	Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
title_short	Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
title_full	Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
title_fullStr	Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
title_full_unstemmed	Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand
title_sort	short practical regimen of acupuncture for melasma: a prospective cohort study in a tertiary hospital in thailand
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/0aa4a3766d6c4bed85f1647b50d39688
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Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand

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