CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock

Abstract Current biomarkers for sepsis are limited by their non-specificity, short half-life, and insensitive response to therapy. Recently, we have demonstrated that citrullinated histone H3(CitH3) is released into the blood from neutrophil extracellular traps(NETs) in response to severe infection,...

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Autores principales: Baihong Pan, Hasan B. Alam, Wei Chong, James Mobley, Baoling Liu, Qiufang Deng, Yinjian Liang, Yanming Wang, Eric Chen, Tianbing Wang, Muneesh Tewari, Yongqing Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0aab2b3818fa475fbc953f16e0260f02
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