In situ click chemistry generation of cyclooxygenase-2 inhibitors

In situ click chemistry generation of cyclooxygenase-2 inhibitors

Traditional inflammation and pain relief drugs target both cyclooxygenase 1 and 2 (COX-1 and COX-2), causing severe side effects. Here, the authors use in situ click chemistry to develop COX-2 specific inhibitors with high in vivo anti-inflammatory activity.

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Autores principales: Atul Bhardwaj, Jatinder Kaur, Melinda Wuest, Frank Wuest
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/0aaf6cbf6f6f49aab5b878a4d847aa9e
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