A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses.

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses.

CD4+ T cell-mediated immunity plays a central role in determining the immunopathogenesis of viral infections. However, the role of CD4+ T cells in EV71 infection, which causes hand, foot and mouth disease (HFMD), has yet to be elucidated. We applied a sophisticated method to identify promiscuous CD4...

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Autores principales: Ruicheng Wei, Chunfu Yang, Mei Zeng, Frances Terry, Kai Zhu, Chunhui Yang, Ralf Altmeyer, William Martin, Anne S De Groot, Qibin Leng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0ab7a891667943df897793627a69b871
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