Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling

Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.

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Detalles Bibliográficos
Autores principales: JongOne Im, Sovan Biswas, Hao Liu, Yanan Zhao, Suman Sen, Sudipta Biswas, Brian Ashcroft, Chad Borges, Xu Wang, Stuart Lindsay, Peiming Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0abe2c2849774ba6a3d78773e2acb03d
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Descripción
Sumario:Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.