Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling

Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.

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Autores principales: JongOne Im, Sovan Biswas, Hao Liu, Yanan Zhao, Suman Sen, Sudipta Biswas, Brian Ashcroft, Chad Borges, Xu Wang, Stuart Lindsay, Peiming Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0abe2c2849774ba6a3d78773e2acb03d
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spelling oai:doaj.org-article:0abe2c2849774ba6a3d78773e2acb03d2021-12-02T16:57:59ZElectronic single-molecule identification of carbohydrate isomers by recognition tunnelling10.1038/ncomms138682041-1723https://doaj.org/article/0abe2c2849774ba6a3d78773e2acb03d2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13868https://doaj.org/toc/2041-1723Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.JongOne ImSovan BiswasHao LiuYanan ZhaoSuman SenSudipta BiswasBrian AshcroftChad BorgesXu WangStuart LindsayPeiming ZhangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
JongOne Im
Sovan Biswas
Hao Liu
Yanan Zhao
Suman Sen
Sudipta Biswas
Brian Ashcroft
Chad Borges
Xu Wang
Stuart Lindsay
Peiming Zhang
Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
description Carbohydrates are common biological molecules, but display huge stereochemical complexity that often cannot be elucidated by mass spectrometry. Here the authors show that recognition tunnelling can distinguish individual stereoisomers, utilizing picomole quantities of analytes.
format article
author JongOne Im
Sovan Biswas
Hao Liu
Yanan Zhao
Suman Sen
Sudipta Biswas
Brian Ashcroft
Chad Borges
Xu Wang
Stuart Lindsay
Peiming Zhang
author_facet JongOne Im
Sovan Biswas
Hao Liu
Yanan Zhao
Suman Sen
Sudipta Biswas
Brian Ashcroft
Chad Borges
Xu Wang
Stuart Lindsay
Peiming Zhang
author_sort JongOne Im
title Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_short Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_full Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_fullStr Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_full_unstemmed Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
title_sort electronic single-molecule identification of carbohydrate isomers by recognition tunnelling
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/0abe2c2849774ba6a3d78773e2acb03d
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