Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress.
The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine protease called PfSUB1, whilst the enclosing PV and...
Guardado en:
Autores principales: | Christine R Collins, Fiona Hackett, Malcolm Strath, Maria Penzo, Chrislaine Withers-Martinez, David A Baker, Michael J Blackman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0ac5d59a497342cd85a38a3530f38e38 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
<i>Plasmodium falciparum</i>
Guanylyl Cyclase-Alpha and the Activity of Its Appended P4-ATPase Domain Are Essential for cGMP Synthesis and Blood-Stage Egress
por: Stephanie D. Nofal, et al.
Publicado: (2021) -
High-throughput screening of the Plasmodium falciparum cGMP-dependent protein kinase identified a thiazole scaffold which kills erythrocytic and sexual stage parasites
por: Maria Penzo, et al.
Publicado: (2019) -
Blue fluorescent cGMP sensor for multiparameter fluorescence imaging.
por: Yusuke Niino, et al.
Publicado: (2010) -
Genetic disruption of Plasmodium falciparum Merozoite surface antigen 180 (PfMSA180) suggests an essential role during parasite egress from erythrocytes
por: Vanndita Bahl, et al.
Publicado: (2021) -
The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress
por: Abigail J. Perrin, et al.
Publicado: (2018)