TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

Whether the adult testis harbours a somatic progenitor population is unknown. Here, the authors provide evidence that the testis interstitial cells expressing the transcription factor Tcf21 maintain adult testis homeostasis during aging, and act as potential reserve somatic progenitors following inj...

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Autores principales: Yu-chi Shen, Adrienne Niederriter Shami, Lindsay Moritz, Hailey Larose, Gabriel L. Manske, Qianyi Ma, Xianing Zheng, Meena Sukhwani, Michael Czerwinski, Caleb Sultan, Haolin Chen, Stephen J. Gurczynski, Jason R. Spence, Kyle E. Orwig, Michelle Tallquist, Jun Z. Li, Saher Sue Hammoud
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0ad48386d6e94016bc9c108c31f26ee9
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