Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography

Purpose: To evaluate the precision of individual and combined macula and optic disc volumetric analysis, and the agreement between these two scan modes with spectral domain optical coherence tomography (OCT).Methods: Macular and optic disc volumetric measurements were performed with individual and c...

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Autores principales:	Alberto Domínguez-Vicent, Jesper Kensén, Marika Wahlberg Ramsay, Rune Brautaset, Abinaya Priya Venkataraman
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	optical coherence tomography volumetric measurement precision agreement simultaneous imaging Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0ad9e984069b4b75b7872534c6018bcf
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spelling	oai:doaj.org-article:0ad9e984069b4b75b7872534c6018bcf2021-12-01T00:16:58ZPrecision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography2296-858X10.3389/fmed.2021.764236https://doaj.org/article/0ad9e984069b4b75b7872534c6018bcf2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.764236/fullhttps://doaj.org/toc/2296-858XPurpose: To evaluate the precision of individual and combined macula and optic disc volumetric analysis, and the agreement between these two scan modes with spectral domain optical coherence tomography (OCT).Methods: Macular and optic disc volumetric measurements were performed with individual and combined scan protocols in one eye of 75 healthy subjects. Three repeated measurements were performed with each protocol. From the macular area, retinal thickness in nine different sectors and ganglion cell complex thickness in eight different sectors were analyzed from both scan modes. From the optic disc area, the peripapillary retinal nerve fiber layer (pRNFL) thickness in 12 clock sectors and the optic disc parameters were evaluated. For all the parameters, repeatability limit and agreement analysis were performed.Results: For the retinal thickness measurements in macula, the combined scan had two to three times larger repeatability limit than the individual scan for all the sectors except the central sector, where the repeatability limit was five times larger. The limits of agreement intervals were lower than 20 μm for all sectors, except the central. The ganglion cell complex measurements also had larger repeatability limits for the combined scans, and the limits of agreement intervals were <10 μm for all sectors. For the pRNFL thickness, the repeatability values were distributed like a vertically elongated ellipse for both scans, but still the repeatability was better for individual scan compared to the combined scan. The shortest and widest interval are obtained for sectors 9 (9 μm) and 12 (40 μm), respectively. The repeatability limit was <0.15 units for all disc parameters with both scan modes.Conclusion: The individual macula and optic disc scans had better repeatability than the combined scan mode, and the two scan modes cannot be used interchangeability due to the wide limits of agreement.Alberto Domínguez-VicentJesper KensénMarika Wahlberg RamsayRune BrautasetAbinaya Priya VenkataramanFrontiers Media S.A.articleoptical coherence tomographyvolumetric measurementprecisionagreementsimultaneous imagingMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	optical coherence tomography volumetric measurement precision agreement simultaneous imaging Medicine (General) R5-920
spellingShingle	optical coherence tomography volumetric measurement precision agreement simultaneous imaging Medicine (General) R5-920 Alberto Domínguez-Vicent Jesper Kensén Marika Wahlberg Ramsay Rune Brautaset Abinaya Priya Venkataraman Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
description	Purpose: To evaluate the precision of individual and combined macula and optic disc volumetric analysis, and the agreement between these two scan modes with spectral domain optical coherence tomography (OCT).Methods: Macular and optic disc volumetric measurements were performed with individual and combined scan protocols in one eye of 75 healthy subjects. Three repeated measurements were performed with each protocol. From the macular area, retinal thickness in nine different sectors and ganglion cell complex thickness in eight different sectors were analyzed from both scan modes. From the optic disc area, the peripapillary retinal nerve fiber layer (pRNFL) thickness in 12 clock sectors and the optic disc parameters were evaluated. For all the parameters, repeatability limit and agreement analysis were performed.Results: For the retinal thickness measurements in macula, the combined scan had two to three times larger repeatability limit than the individual scan for all the sectors except the central sector, where the repeatability limit was five times larger. The limits of agreement intervals were lower than 20 μm for all sectors, except the central. The ganglion cell complex measurements also had larger repeatability limits for the combined scans, and the limits of agreement intervals were <10 μm for all sectors. For the pRNFL thickness, the repeatability values were distributed like a vertically elongated ellipse for both scans, but still the repeatability was better for individual scan compared to the combined scan. The shortest and widest interval are obtained for sectors 9 (9 μm) and 12 (40 μm), respectively. The repeatability limit was <0.15 units for all disc parameters with both scan modes.Conclusion: The individual macula and optic disc scans had better repeatability than the combined scan mode, and the two scan modes cannot be used interchangeability due to the wide limits of agreement.
format	article
author	Alberto Domínguez-Vicent Jesper Kensén Marika Wahlberg Ramsay Rune Brautaset Abinaya Priya Venkataraman
author_facet	Alberto Domínguez-Vicent Jesper Kensén Marika Wahlberg Ramsay Rune Brautaset Abinaya Priya Venkataraman
author_sort	Alberto Domínguez-Vicent
title	Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
title_short	Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
title_full	Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
title_fullStr	Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
title_full_unstemmed	Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography
title_sort	precision and agreement of individual and simultaneous macular and optic disc volumetric measurements with spectral domain optical coherence tomography
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/0ad9e984069b4b75b7872534c6018bcf
work_keys_str_mv	AT albertodominguezvicent precisionandagreementofindividualandsimultaneousmacularandopticdiscvolumetricmeasurementswithspectraldomainopticalcoherencetomography AT jesperkensen precisionandagreementofindividualandsimultaneousmacularandopticdiscvolumetricmeasurementswithspectraldomainopticalcoherencetomography AT marikawahlbergramsay precisionandagreementofindividualandsimultaneousmacularandopticdiscvolumetricmeasurementswithspectraldomainopticalcoherencetomography AT runebrautaset precisionandagreementofindividualandsimultaneousmacularandopticdiscvolumetricmeasurementswithspectraldomainopticalcoherencetomography AT abinayapriyavenkataraman precisionandagreementofindividualandsimultaneousmacularandopticdiscvolumetricmeasurementswithspectraldomainopticalcoherencetomography
_version_	1718406003330908160

Precision and Agreement of Individual and Simultaneous Macular and Optic Disc Volumetric Measurements With Spectral Domain Optical Coherence Tomography

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