Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls.
Guardado en:
Autores principales: | , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c11950 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0adb2f6ba5da4fa2b773af4b00c11950 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0adb2f6ba5da4fa2b773af4b00c119502021-12-02T15:35:50ZReduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging10.1038/s41467-019-12366-42041-1723https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c119502019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12366-4https://doaj.org/toc/2041-1723Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls.Abhishekh H. AshokJim MyersTiago Reis MarquesEugenii A. RabinerOliver D. HowesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Abhishekh H. Ashok Jim Myers Tiago Reis Marques Eugenii A. Rabiner Oliver D. Howes Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
description |
Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls. |
format |
article |
author |
Abhishekh H. Ashok Jim Myers Tiago Reis Marques Eugenii A. Rabiner Oliver D. Howes |
author_facet |
Abhishekh H. Ashok Jim Myers Tiago Reis Marques Eugenii A. Rabiner Oliver D. Howes |
author_sort |
Abhishekh H. Ashok |
title |
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
title_short |
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
title_full |
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
title_fullStr |
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
title_full_unstemmed |
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging |
title_sort |
reduced mu opioid receptor availability in schizophrenia revealed with [11c]-carfentanil positron emission tomographic imaging |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c11950 |
work_keys_str_mv |
AT abhishekhhashok reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging AT jimmyers reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging AT tiagoreismarques reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging AT eugeniiarabiner reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging AT oliverdhowes reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging |
_version_ |
1718386393330221056 |