Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging

Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls.

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Autores principales: Abhishekh H. Ashok, Jim Myers, Tiago Reis Marques, Eugenii A. Rabiner, Oliver D. Howes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c11950
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spelling oai:doaj.org-article:0adb2f6ba5da4fa2b773af4b00c119502021-12-02T15:35:50ZReduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging10.1038/s41467-019-12366-42041-1723https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c119502019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12366-4https://doaj.org/toc/2041-1723Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls.Abhishekh H. AshokJim MyersTiago Reis MarquesEugenii A. RabinerOliver D. HowesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Abhishekh H. Ashok
Jim Myers
Tiago Reis Marques
Eugenii A. Rabiner
Oliver D. Howes
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
description Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR compared to controls.
format article
author Abhishekh H. Ashok
Jim Myers
Tiago Reis Marques
Eugenii A. Rabiner
Oliver D. Howes
author_facet Abhishekh H. Ashok
Jim Myers
Tiago Reis Marques
Eugenii A. Rabiner
Oliver D. Howes
author_sort Abhishekh H. Ashok
title Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
title_short Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
title_full Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
title_fullStr Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
title_full_unstemmed Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
title_sort reduced mu opioid receptor availability in schizophrenia revealed with [11c]-carfentanil positron emission tomographic imaging
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/0adb2f6ba5da4fa2b773af4b00c11950
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AT tiagoreismarques reducedmuopioidreceptoravailabilityinschizophreniarevealedwith11ccarfentanilpositronemissiontomographicimaging
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