Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer
Signet-ring cell carcinoma (SRCC) is a unique type of gastric cancer with no prognostic features. Here, the authors report a CLDN18-ARHGAP26/6 gene fusion in patients with a high signet-ring cell content, poor survival outcomes, and who experience no benefit from platinum/fluoropyrimidines-based che...
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Nature Portfolio
2018
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oai:doaj.org-article:0af28044d4f140f487a94c56751ce5f02021-12-02T14:38:49ZPrognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer10.1038/s41467-018-04907-02041-1723https://doaj.org/article/0af28044d4f140f487a94c56751ce5f02018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04907-0https://doaj.org/toc/2041-1723Signet-ring cell carcinoma (SRCC) is a unique type of gastric cancer with no prognostic features. Here, the authors report a CLDN18-ARHGAP26/6 gene fusion in patients with a high signet-ring cell content, poor survival outcomes, and who experience no benefit from platinum/fluoropyrimidines-based chemotherapy.Yang ShuWeihan ZhangQianqian HouLinyong ZhaoShouyue ZhangJiankang ZhouXiaohai SongYan ZhangDan JiangXinzu ChenPeiqi WangXuyang XiaFei LiaoDandan YinXiaolong ChenXueyan ZhouDuyu ZhangSenlin YinKun YangJianping LiuLeilei FuLan ZhangYuelan WangJunlong ZhangYunfei AnHua ChengBin ZhengHongye SunYinglan ZhaoYongsheng WangDan XieLiang OuyangPing WangWei ZhangMeng QiuXianghui FuLunzhi DaiGu HeHanshuo YangWei ChengLi YangBo LiuWeimin LiBiao DongZongguang ZhouYuquan WeiYong PengHeng XuJiankun HuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Yang Shu Weihan Zhang Qianqian Hou Linyong Zhao Shouyue Zhang Jiankang Zhou Xiaohai Song Yan Zhang Dan Jiang Xinzu Chen Peiqi Wang Xuyang Xia Fei Liao Dandan Yin Xiaolong Chen Xueyan Zhou Duyu Zhang Senlin Yin Kun Yang Jianping Liu Leilei Fu Lan Zhang Yuelan Wang Junlong Zhang Yunfei An Hua Cheng Bin Zheng Hongye Sun Yinglan Zhao Yongsheng Wang Dan Xie Liang Ouyang Ping Wang Wei Zhang Meng Qiu Xianghui Fu Lunzhi Dai Gu He Hanshuo Yang Wei Cheng Li Yang Bo Liu Weimin Li Biao Dong Zongguang Zhou Yuquan Wei Yong Peng Heng Xu Jiankun Hu Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| description |
Signet-ring cell carcinoma (SRCC) is a unique type of gastric cancer with no prognostic features. Here, the authors report a CLDN18-ARHGAP26/6 gene fusion in patients with a high signet-ring cell content, poor survival outcomes, and who experience no benefit from platinum/fluoropyrimidines-based chemotherapy. |
| format |
article |
| author |
Yang Shu Weihan Zhang Qianqian Hou Linyong Zhao Shouyue Zhang Jiankang Zhou Xiaohai Song Yan Zhang Dan Jiang Xinzu Chen Peiqi Wang Xuyang Xia Fei Liao Dandan Yin Xiaolong Chen Xueyan Zhou Duyu Zhang Senlin Yin Kun Yang Jianping Liu Leilei Fu Lan Zhang Yuelan Wang Junlong Zhang Yunfei An Hua Cheng Bin Zheng Hongye Sun Yinglan Zhao Yongsheng Wang Dan Xie Liang Ouyang Ping Wang Wei Zhang Meng Qiu Xianghui Fu Lunzhi Dai Gu He Hanshuo Yang Wei Cheng Li Yang Bo Liu Weimin Li Biao Dong Zongguang Zhou Yuquan Wei Yong Peng Heng Xu Jiankun Hu |
| author_facet |
Yang Shu Weihan Zhang Qianqian Hou Linyong Zhao Shouyue Zhang Jiankang Zhou Xiaohai Song Yan Zhang Dan Jiang Xinzu Chen Peiqi Wang Xuyang Xia Fei Liao Dandan Yin Xiaolong Chen Xueyan Zhou Duyu Zhang Senlin Yin Kun Yang Jianping Liu Leilei Fu Lan Zhang Yuelan Wang Junlong Zhang Yunfei An Hua Cheng Bin Zheng Hongye Sun Yinglan Zhao Yongsheng Wang Dan Xie Liang Ouyang Ping Wang Wei Zhang Meng Qiu Xianghui Fu Lunzhi Dai Gu He Hanshuo Yang Wei Cheng Li Yang Bo Liu Weimin Li Biao Dong Zongguang Zhou Yuquan Wei Yong Peng Heng Xu Jiankun Hu |
| author_sort |
Yang Shu |
| title |
Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| title_short |
Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| title_full |
Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| title_fullStr |
Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| title_full_unstemmed |
Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer |
| title_sort |
prognostic significance of frequent cldn18-arhgap26/6 fusion in gastric signet-ring cell cancer |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/0af28044d4f140f487a94c56751ce5f0 |
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