Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections

Abstract Acoustic tweezing of bioparticles has distinct advantages over other manipulation methods such as electrophoresis or magnetophoresis in biotechnological applications. This manipulation method guarantees the viability of the bio-particles during and after the process. In this paper, the effe...

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Autores principales:	Elnaz Attar Jannesar, Hossein Hamzehpour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0afb3b05c8694399a9433f9408f056ce
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spelling	oai:doaj.org-article:0afb3b05c8694399a9433f9408f056ce2021-12-02T17:41:12ZAcoustic tweezing of microparticles in microchannels with sinusoidal cross sections10.1038/s41598-021-97132-72045-2322https://doaj.org/article/0afb3b05c8694399a9433f9408f056ce2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97132-7https://doaj.org/toc/2045-2322Abstract Acoustic tweezing of bioparticles has distinct advantages over other manipulation methods such as electrophoresis or magnetophoresis in biotechnological applications. This manipulation method guarantees the viability of the bio-particles during and after the process. In this paper, the effects of sinusoidal boundaries of a microchannel on acoustophoretic manipulation of microparticles are studied. Our results show that while top and bottom walls are vertically actuated at the horizontal half-wave resonance frequency, a large mono-vortex appears, which is never achievable in a rectangular geometry with flat walls and one-dimensional oscillations. The drag force caused by such a vortex in combination with the tilted acoustic radiation force leads to trapping and micromixing of microparticles with diameters larger and smaller than the critical size, respectively. Simulation results in this paper show that efficient particle trapping occurs at the intermediate sinusoidal boundary amplitudes. It is also indicated that in a square-sinusoidal geometry there are two strong vortices, instead of one vortex. Sub-micrometer particles tend to be trapped dramatically faster in such a geometry than in the rectangular-sinusoidal ones.Elnaz Attar JannesarHossein HamzehpourNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Elnaz Attar Jannesar Hossein Hamzehpour Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
description	Abstract Acoustic tweezing of bioparticles has distinct advantages over other manipulation methods such as electrophoresis or magnetophoresis in biotechnological applications. This manipulation method guarantees the viability of the bio-particles during and after the process. In this paper, the effects of sinusoidal boundaries of a microchannel on acoustophoretic manipulation of microparticles are studied. Our results show that while top and bottom walls are vertically actuated at the horizontal half-wave resonance frequency, a large mono-vortex appears, which is never achievable in a rectangular geometry with flat walls and one-dimensional oscillations. The drag force caused by such a vortex in combination with the tilted acoustic radiation force leads to trapping and micromixing of microparticles with diameters larger and smaller than the critical size, respectively. Simulation results in this paper show that efficient particle trapping occurs at the intermediate sinusoidal boundary amplitudes. It is also indicated that in a square-sinusoidal geometry there are two strong vortices, instead of one vortex. Sub-micrometer particles tend to be trapped dramatically faster in such a geometry than in the rectangular-sinusoidal ones.
format	article
author	Elnaz Attar Jannesar Hossein Hamzehpour
author_facet	Elnaz Attar Jannesar Hossein Hamzehpour
author_sort	Elnaz Attar Jannesar
title	Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
title_short	Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
title_full	Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
title_fullStr	Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
title_full_unstemmed	Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
title_sort	acoustic tweezing of microparticles in microchannels with sinusoidal cross sections
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0afb3b05c8694399a9433f9408f056ce
work_keys_str_mv	AT elnazattarjannesar acoustictweezingofmicroparticlesinmicrochannelswithsinusoidalcrosssections AT hosseinhamzehpour acoustictweezingofmicroparticlesinmicrochannelswithsinusoidalcrosssections
_version_	1718379688866349056

Acoustic tweezing of microparticles in microchannels with sinusoidal cross sections

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