Cyclophosphamide abrogates the expansion of CD4+Foxp3+ regulatory T cells and enhances the efficacy of bleomycin in the treatment of mouse B16-F10 melanomas
Objective: Promotion of the proliferative expansion of CD4+Foxp3+ regulatory T cells (Tregs) is one of the side effects that limits the use of bleomycin (BLM) in the treatment of tumors. In this study, we examined the hypothesis that cyclophosphamide (CY), a chemotherapeutic agent with the capacity...
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Autores principales: | Ping Li, Fengyang Chen, Jingbin Zheng, Yang Yang, Yuan Li, Yifei Wang, Xin Chen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
China Anti-Cancer Association
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/0afc7b65b64c49c7b4d5bfdf3c71892c |
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