Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
An increase in the volume of the brain lateral ventricles is a sign of normal aging, but can also be associated with neurological and psychiatric disorders. Here, Vojinovic et al. identify seven genetic loci in a GWA study for ventricular volume in 23,500 individuals and find correlation with thalam...
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Nature Portfolio
2018
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oai:doaj.org-article:0b047876c51c45fea748659ec62d0c252021-12-02T17:32:45ZGenome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume10.1038/s41467-018-06234-w2041-1723https://doaj.org/article/0b047876c51c45fea748659ec62d0c252018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06234-whttps://doaj.org/toc/2041-1723An increase in the volume of the brain lateral ventricles is a sign of normal aging, but can also be associated with neurological and psychiatric disorders. Here, Vojinovic et al. identify seven genetic loci in a GWA study for ventricular volume in 23,500 individuals and find correlation with thalamus volume.Dina VojinovicHieab H. AdamsXueqiu JianQiong YangAlbert Vernon SmithJoshua C. BisAlexander TeumerMarkus ScholzNicola J. ArmstrongEdith HoferYasaman SabaMichelle LucianoManon BernardStella TrompetJingyun YangNathan A. GillespieSven J. van der LeeAlexander NeumannShahzad AhmadOle A. AndreassenDavid AmesNajaf AminKonstantinos ArfanakisMark E. BastinDiane M. BeckerAlexa S. BeiserFrauke BeyerHenry BrodatyR. Nick BryanRobin BülowAnders M. DalePhilip L. De JagerIan J. DearyCharles DeCarliDebra A. FleischmanRebecca F. GottesmanJeroen van der GrondVilmundur GudnasonTamara B. HarrisGeorg HomuthDavid S. KnopmanJohn B. KwokCora E. LewisShuo LiMarkus LoefflerOscar L. LopezPauline MaillardHanan El MarrounKaren A. MatherThomas H. MosleyRyan L. MuetzelMatthias NauckPaul A. NyquistMatthew S. PanizzonZdenka PausovaBruce M. PsatyKen RiceJerome I. RotterNatalie RoyleClaudia L. SatizabalReinhold SchmidtPeter R. SchofieldPamela J. SchreinerStephen SidneyDavid J. StottAnbupalam ThalamuthuAndre G. UitterlindenMaria C. Valdés HernándezMeike W. VernooijWei WenTonya WhiteA. Veronica WitteKatharina WittfeldMargaret J. WrightLisa R. YanekHenning TiemeierWilliam S. KremenDavid A. BennettJ. Wouter JukemaTomas PausJoanna M. WardlawHelena SchmidtPerminder S. SachdevArno VillringerHans Jörgen GrabeW T LongstrethCornelia M. van DuijnLenore J. LaunerSudha SeshadriM Arfan IkramMyriam FornageNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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DOAJ |
| collection |
DOAJ |
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EN |
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Science Q |
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Science Q Dina Vojinovic Hieab H. Adams Xueqiu Jian Qiong Yang Albert Vernon Smith Joshua C. Bis Alexander Teumer Markus Scholz Nicola J. Armstrong Edith Hofer Yasaman Saba Michelle Luciano Manon Bernard Stella Trompet Jingyun Yang Nathan A. Gillespie Sven J. van der Lee Alexander Neumann Shahzad Ahmad Ole A. Andreassen David Ames Najaf Amin Konstantinos Arfanakis Mark E. Bastin Diane M. Becker Alexa S. Beiser Frauke Beyer Henry Brodaty R. Nick Bryan Robin Bülow Anders M. Dale Philip L. De Jager Ian J. Deary Charles DeCarli Debra A. Fleischman Rebecca F. Gottesman Jeroen van der Grond Vilmundur Gudnason Tamara B. Harris Georg Homuth David S. Knopman John B. Kwok Cora E. Lewis Shuo Li Markus Loeffler Oscar L. Lopez Pauline Maillard Hanan El Marroun Karen A. Mather Thomas H. Mosley Ryan L. Muetzel Matthias Nauck Paul A. Nyquist Matthew S. Panizzon Zdenka Pausova Bruce M. Psaty Ken Rice Jerome I. Rotter Natalie Royle Claudia L. Satizabal Reinhold Schmidt Peter R. Schofield Pamela J. Schreiner Stephen Sidney David J. Stott Anbupalam Thalamuthu Andre G. Uitterlinden Maria C. Valdés Hernández Meike W. Vernooij Wei Wen Tonya White A. Veronica Witte Katharina Wittfeld Margaret J. Wright Lisa R. Yanek Henning Tiemeier William S. Kremen David A. Bennett J. Wouter Jukema Tomas Paus Joanna M. Wardlaw Helena Schmidt Perminder S. Sachdev Arno Villringer Hans Jörgen Grabe W T Longstreth Cornelia M. van Duijn Lenore J. Launer Sudha Seshadri M Arfan Ikram Myriam Fornage Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| description |
An increase in the volume of the brain lateral ventricles is a sign of normal aging, but can also be associated with neurological and psychiatric disorders. Here, Vojinovic et al. identify seven genetic loci in a GWA study for ventricular volume in 23,500 individuals and find correlation with thalamus volume. |
| format |
article |
| author |
Dina Vojinovic Hieab H. Adams Xueqiu Jian Qiong Yang Albert Vernon Smith Joshua C. Bis Alexander Teumer Markus Scholz Nicola J. Armstrong Edith Hofer Yasaman Saba Michelle Luciano Manon Bernard Stella Trompet Jingyun Yang Nathan A. Gillespie Sven J. van der Lee Alexander Neumann Shahzad Ahmad Ole A. Andreassen David Ames Najaf Amin Konstantinos Arfanakis Mark E. Bastin Diane M. Becker Alexa S. Beiser Frauke Beyer Henry Brodaty R. Nick Bryan Robin Bülow Anders M. Dale Philip L. De Jager Ian J. Deary Charles DeCarli Debra A. Fleischman Rebecca F. Gottesman Jeroen van der Grond Vilmundur Gudnason Tamara B. Harris Georg Homuth David S. Knopman John B. Kwok Cora E. Lewis Shuo Li Markus Loeffler Oscar L. Lopez Pauline Maillard Hanan El Marroun Karen A. Mather Thomas H. Mosley Ryan L. Muetzel Matthias Nauck Paul A. Nyquist Matthew S. Panizzon Zdenka Pausova Bruce M. Psaty Ken Rice Jerome I. Rotter Natalie Royle Claudia L. Satizabal Reinhold Schmidt Peter R. Schofield Pamela J. Schreiner Stephen Sidney David J. Stott Anbupalam Thalamuthu Andre G. Uitterlinden Maria C. Valdés Hernández Meike W. Vernooij Wei Wen Tonya White A. Veronica Witte Katharina Wittfeld Margaret J. Wright Lisa R. Yanek Henning Tiemeier William S. Kremen David A. Bennett J. Wouter Jukema Tomas Paus Joanna M. Wardlaw Helena Schmidt Perminder S. Sachdev Arno Villringer Hans Jörgen Grabe W T Longstreth Cornelia M. van Duijn Lenore J. Launer Sudha Seshadri M Arfan Ikram Myriam Fornage |
| author_facet |
Dina Vojinovic Hieab H. Adams Xueqiu Jian Qiong Yang Albert Vernon Smith Joshua C. Bis Alexander Teumer Markus Scholz Nicola J. Armstrong Edith Hofer Yasaman Saba Michelle Luciano Manon Bernard Stella Trompet Jingyun Yang Nathan A. Gillespie Sven J. van der Lee Alexander Neumann Shahzad Ahmad Ole A. Andreassen David Ames Najaf Amin Konstantinos Arfanakis Mark E. Bastin Diane M. Becker Alexa S. Beiser Frauke Beyer Henry Brodaty R. Nick Bryan Robin Bülow Anders M. Dale Philip L. De Jager Ian J. Deary Charles DeCarli Debra A. Fleischman Rebecca F. Gottesman Jeroen van der Grond Vilmundur Gudnason Tamara B. Harris Georg Homuth David S. Knopman John B. Kwok Cora E. Lewis Shuo Li Markus Loeffler Oscar L. Lopez Pauline Maillard Hanan El Marroun Karen A. Mather Thomas H. Mosley Ryan L. Muetzel Matthias Nauck Paul A. Nyquist Matthew S. Panizzon Zdenka Pausova Bruce M. Psaty Ken Rice Jerome I. Rotter Natalie Royle Claudia L. Satizabal Reinhold Schmidt Peter R. Schofield Pamela J. Schreiner Stephen Sidney David J. Stott Anbupalam Thalamuthu Andre G. Uitterlinden Maria C. Valdés Hernández Meike W. Vernooij Wei Wen Tonya White A. Veronica Witte Katharina Wittfeld Margaret J. Wright Lisa R. Yanek Henning Tiemeier William S. Kremen David A. Bennett J. Wouter Jukema Tomas Paus Joanna M. Wardlaw Helena Schmidt Perminder S. Sachdev Arno Villringer Hans Jörgen Grabe W T Longstreth Cornelia M. van Duijn Lenore J. Launer Sudha Seshadri M Arfan Ikram Myriam Fornage |
| author_sort |
Dina Vojinovic |
| title |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| title_short |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| title_full |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| title_fullStr |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| title_full_unstemmed |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| title_sort |
genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/0b047876c51c45fea748659ec62d0c25 |
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