Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures
Historical interbreeding between Neanderthals and humans should leave signatures of historical demographics in modern human genomes. Analysing the size distribution of Neanderthal fragments in non-African genomes suggests consistent differences in the generation interval across Eurasia, and that thi...
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2021
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oai:doaj.org-article:0b080f9ae07b4797accda7ddfbebf81b2021-12-02T17:42:05ZDifferent historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures10.1038/s41467-021-25524-42041-1723https://doaj.org/article/0b080f9ae07b4797accda7ddfbebf81b2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25524-4https://doaj.org/toc/2041-1723Historical interbreeding between Neanderthals and humans should leave signatures of historical demographics in modern human genomes. Analysing the size distribution of Neanderthal fragments in non-African genomes suggests consistent differences in the generation interval across Eurasia, and that this could explain mutational spectrum variation.Moisès Coll MaciàLaurits SkovBenjamin Marco PeterMikkel Heide SchierupNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
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Science Q Moisès Coll Macià Laurits Skov Benjamin Marco Peter Mikkel Heide Schierup Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
description |
Historical interbreeding between Neanderthals and humans should leave signatures of historical demographics in modern human genomes. Analysing the size distribution of Neanderthal fragments in non-African genomes suggests consistent differences in the generation interval across Eurasia, and that this could explain mutational spectrum variation. |
format |
article |
author |
Moisès Coll Macià Laurits Skov Benjamin Marco Peter Mikkel Heide Schierup |
author_facet |
Moisès Coll Macià Laurits Skov Benjamin Marco Peter Mikkel Heide Schierup |
author_sort |
Moisès Coll Macià |
title |
Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
title_short |
Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
title_full |
Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
title_fullStr |
Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
title_full_unstemmed |
Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures |
title_sort |
different historical generation intervals in human populations inferred from neanderthal fragment lengths and mutation signatures |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0b080f9ae07b4797accda7ddfbebf81b |
work_keys_str_mv |
AT moisescollmacia differenthistoricalgenerationintervalsinhumanpopulationsinferredfromneanderthalfragmentlengthsandmutationsignatures AT lauritsskov differenthistoricalgenerationintervalsinhumanpopulationsinferredfromneanderthalfragmentlengthsandmutationsignatures AT benjaminmarcopeter differenthistoricalgenerationintervalsinhumanpopulationsinferredfromneanderthalfragmentlengthsandmutationsignatures AT mikkelheideschierup differenthistoricalgenerationintervalsinhumanpopulationsinferredfromneanderthalfragmentlengthsandmutationsignatures |
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