Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis

Abstract Aryl polyenes (APE) are one of the most widespread secondary metabolites among gram-negative bacteria. In Acinetobacter baumannii, strains belonging to the virulent global clone 2 (GC2) mostly contain APE biosynthesis genes; its relevance in elevated pathogenicity is of great interest. APE...

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Auteurs principaux: Woo Cheol Lee, Sungjae Choi, Ahjin Jang, Jiwon Yeon, Eunha Hwang, Yangmee Kim
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0b0ca0feb3a945c29e20ebff5b53018e
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