Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness

Abstract Essential oils are natural products that have great antimicrobial potential value against many fungi and bacteria. Rosa damascena Mill. is one of the most important aromatic species of the Rosaceae family from which essential oil and economically valuable products can be obtained. The prese...

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Autores principales:	Mansureh Ghavam, Afsaneh Afzali, Maria Letizia Manca
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0b0cb6b16be4413ea7dcc95acb7bb422
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spelling	oai:doaj.org-article:0b0cb6b16be4413ea7dcc95acb7bb4222021-12-02T18:03:46ZChemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness10.1038/s41598-021-87604-12045-2322https://doaj.org/article/0b0cb6b16be4413ea7dcc95acb7bb4222021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87604-1https://doaj.org/toc/2045-2322Abstract Essential oils are natural products that have great antimicrobial potential value against many fungi and bacteria. Rosa damascena Mill. is one of the most important aromatic species of the Rosaceae family from which essential oil and economically valuable products can be obtained. The present study was designed to investigate the major compositions of the essential oil of this plant in Isfahan region of Iran and to identify its antibacterial and antifungal effects against 11 microorganisms causing human diseases and food spoilage. The essential oil was extracted by using the Clevenger apparatus and was analyzed by gas chromatography-mass spectrometry (GC–MS) technique. Its antimicrobial activity was evaluated by well diffusion, minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC). The results showed that the most important compounds of the essential oil were nonadecane (24.72%), heneicosane (19.325%), oleic acid (17.63%), and citronellol (12.61%). The results also showed that the highest inhibition zone of rose essential oil was against Aspergillus brasiliensis (15.00 ± 0.00 mm) and had a significant effect on Klebsiella pneumoniae (~ 8.00 mm). Also the rose oil had a significant inhibition and lethal effect against Candida albicans (MIC and MBC ~ 125 μg/mL), which is equivalent to the nystatin antibiotic (~ 125 μg/mL). Therefore, the essential oil of Damask rose can be considered as an alternative natural product for the prevention and treatment of fungal diseases in humans and against food spoilage as well.Mansureh GhavamAfsaneh AfzaliMaria Letizia MancaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mansureh Ghavam Afsaneh Afzali Maria Letizia Manca Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
description	Abstract Essential oils are natural products that have great antimicrobial potential value against many fungi and bacteria. Rosa damascena Mill. is one of the most important aromatic species of the Rosaceae family from which essential oil and economically valuable products can be obtained. The present study was designed to investigate the major compositions of the essential oil of this plant in Isfahan region of Iran and to identify its antibacterial and antifungal effects against 11 microorganisms causing human diseases and food spoilage. The essential oil was extracted by using the Clevenger apparatus and was analyzed by gas chromatography-mass spectrometry (GC–MS) technique. Its antimicrobial activity was evaluated by well diffusion, minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC). The results showed that the most important compounds of the essential oil were nonadecane (24.72%), heneicosane (19.325%), oleic acid (17.63%), and citronellol (12.61%). The results also showed that the highest inhibition zone of rose essential oil was against Aspergillus brasiliensis (15.00 ± 0.00 mm) and had a significant effect on Klebsiella pneumoniae (~ 8.00 mm). Also the rose oil had a significant inhibition and lethal effect against Candida albicans (MIC and MBC ~ 125 μg/mL), which is equivalent to the nystatin antibiotic (~ 125 μg/mL). Therefore, the essential oil of Damask rose can be considered as an alternative natural product for the prevention and treatment of fungal diseases in humans and against food spoilage as well.
format	article
author	Mansureh Ghavam Afsaneh Afzali Maria Letizia Manca
author_facet	Mansureh Ghavam Afsaneh Afzali Maria Letizia Manca
author_sort	Mansureh Ghavam
title	Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
title_short	Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
title_full	Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
title_fullStr	Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
title_full_unstemmed	Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
title_sort	chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0b0cb6b16be4413ea7dcc95acb7bb422
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Chemotype of damask rose with oleic acid (9 octadecenoic acid) and its antimicrobial effectiveness

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