Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma

The standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bor...

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Autores principales: Jiao Cai, Ling Qiu, Lei Ma, Nan Zhang, Fang-yi Fan
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/0b1136c191e8499ba4a5fd84606a74a7
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spelling oai:doaj.org-article:0b1136c191e8499ba4a5fd84606a74a72021-12-03T05:06:29ZCase Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma2296-858X10.3389/fmed.2021.749863https://doaj.org/article/0b1136c191e8499ba4a5fd84606a74a72021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.749863/fullhttps://doaj.org/toc/2296-858XThe standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bortezomib plus cyclophosphamide, epirubicin, vindesine and prednisolone (CDOP) followed by sequential autologous hematopoietic stem cell transplantation (ASCT) and lenalidomide-based maintenance therapy to treat PBL may represent a promising regimen to improve the prognosis.Jiao CaiLing QiuLei MaNan ZhangFang-yi FanFrontiers Media S.A.articleplasmablastic lymphomabortezomiblenalidomideautologous hematopoietic stem cell transplantation18F-FDG PET/CTMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic plasmablastic lymphoma
bortezomib
lenalidomide
autologous hematopoietic stem cell transplantation
18F-FDG PET/CT
Medicine (General)
R5-920
spellingShingle plasmablastic lymphoma
bortezomib
lenalidomide
autologous hematopoietic stem cell transplantation
18F-FDG PET/CT
Medicine (General)
R5-920
Jiao Cai
Ling Qiu
Lei Ma
Nan Zhang
Fang-yi Fan
Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
description The standardized treatment plan for patients with plasmablastic lymphoma (PBL) remains controversial. Taking morphological characteristics and immunophenotypes into consideration may provide superior options for the treatment of PBL. In this case, we report that a myeloma-type regimen containing bortezomib plus cyclophosphamide, epirubicin, vindesine and prednisolone (CDOP) followed by sequential autologous hematopoietic stem cell transplantation (ASCT) and lenalidomide-based maintenance therapy to treat PBL may represent a promising regimen to improve the prognosis.
format article
author Jiao Cai
Ling Qiu
Lei Ma
Nan Zhang
Fang-yi Fan
author_facet Jiao Cai
Ling Qiu
Lei Ma
Nan Zhang
Fang-yi Fan
author_sort Jiao Cai
title Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_short Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_full Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_fullStr Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_full_unstemmed Case Report: Bortezomib Plus CDOP Followed by Sequential Autologous Hematopoietic Stem Cell Transplantation and Lenalidomide-Based Maintenance Therapy in Plasmablastic Lymphoma
title_sort case report: bortezomib plus cdop followed by sequential autologous hematopoietic stem cell transplantation and lenalidomide-based maintenance therapy in plasmablastic lymphoma
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/0b1136c191e8499ba4a5fd84606a74a7
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