Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.

Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.

Fibroblast-like synoviocytes (FLS) play an important role in the pathologic processes of destructive arthritis by producing a number of catabolic cytokines and metalloproteinases (MMPs). The expression of these mediators is controlled at the transcriptional level. The purposes of this study were to...

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Autores principales: Jyh-Horng Wang, Kao-Shang Shih, Jing-Ping Liou, Yi-Wen Wu, Anita Shin-Yuan Chang, Kang-Li Wang, Ching-Lin Tsai, Chia-Ron Yang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0b14adf08bc44d2b98428148d6a65951
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