The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.

<h4>Background</h4>The objectives of this study were to evaluate the influence of iterative reconstruction (IR) on pulmonary nodule volumetry with chest computed tomography (CT).<h4>Methods</h4>Twenty patients (12 women and 8 men, mean age 61.9, range 32-87) underwent evaluat...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Martin J Willemink, Jaap Borstlap, Richard A P Takx, Arnold M R Schilham, Tim Leiner, Ricardo P J Budde, Pim A de Jong
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0b1526671a9b4e379143ab519369b24d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0b1526671a9b4e379143ab519369b24d
record_format	dspace
spelling	oai:doaj.org-article:0b1526671a9b4e379143ab519369b24d2021-11-18T07:55:42ZThe effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.1932-620310.1371/journal.pone.0058053https://doaj.org/article/0b1526671a9b4e379143ab519369b24d2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23460924/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>The objectives of this study were to evaluate the influence of iterative reconstruction (IR) on pulmonary nodule volumetry with chest computed tomography (CT).<h4>Methods</h4>Twenty patients (12 women and 8 men, mean age 61.9, range 32-87) underwent evaluation of pulmonary nodules with a 64-slice CT-scanner. Data were reconstructed using filtered back projection (FBP) and IR (Philips Healthcare, iDose(4)-levels 2, 4 and 6) at similar radiation dose. Volumetric nodule measurements were performed with semi-automatic software on thin slice reconstructions. Only solid pulmonary nodules were measured, no additional selection criteria were used for the nature of nodules. For intra-observer and inter-observer variability, measurements were performed once by one observer and twice by another observer. Algorithms were compared using the concordance correlation-coefficient (pc) and Friedman-test, and post-hoc analysis with the Wilcoxon-signed ranks-test with Bonferroni-correction (significance-level p<0.017).<h4>Results</h4>Seventy-eight nodules were present including 56 small nodules (volume<200 mm(3), diameter<8 mm) and 22 large nodules (volume≥200 mm(3), diameter≥8 mm). No significant differences in measured pulmonary nodule volumes between FBP, iDose(4)-levels 2, 4 and 6 were found in both small nodules and large nodules. FBP and iDose(4)-levels 2, 4 and 6 were correlated with pc-values of 0.98 or higher for both small and large nodules. Pc-values of intra-observer and inter-observer variability were 0.98 or higher.<h4>Conclusions</h4>Measurements of solid pulmonary nodule volume measured with standard-FBP were comparable with IR, regardless of the IR-level and no significant differences between measured volumes of both small and large solid nodules were found.Martin J WilleminkJaap BorstlapRichard A P TakxArnold M R SchilhamTim LeinerRicardo P J BuddePim A de JongPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 2, p e58053 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Martin J Willemink Jaap Borstlap Richard A P Takx Arnold M R Schilham Tim Leiner Ricardo P J Budde Pim A de Jong The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
description	<h4>Background</h4>The objectives of this study were to evaluate the influence of iterative reconstruction (IR) on pulmonary nodule volumetry with chest computed tomography (CT).<h4>Methods</h4>Twenty patients (12 women and 8 men, mean age 61.9, range 32-87) underwent evaluation of pulmonary nodules with a 64-slice CT-scanner. Data were reconstructed using filtered back projection (FBP) and IR (Philips Healthcare, iDose(4)-levels 2, 4 and 6) at similar radiation dose. Volumetric nodule measurements were performed with semi-automatic software on thin slice reconstructions. Only solid pulmonary nodules were measured, no additional selection criteria were used for the nature of nodules. For intra-observer and inter-observer variability, measurements were performed once by one observer and twice by another observer. Algorithms were compared using the concordance correlation-coefficient (pc) and Friedman-test, and post-hoc analysis with the Wilcoxon-signed ranks-test with Bonferroni-correction (significance-level p<0.017).<h4>Results</h4>Seventy-eight nodules were present including 56 small nodules (volume<200 mm(3), diameter<8 mm) and 22 large nodules (volume≥200 mm(3), diameter≥8 mm). No significant differences in measured pulmonary nodule volumes between FBP, iDose(4)-levels 2, 4 and 6 were found in both small nodules and large nodules. FBP and iDose(4)-levels 2, 4 and 6 were correlated with pc-values of 0.98 or higher for both small and large nodules. Pc-values of intra-observer and inter-observer variability were 0.98 or higher.<h4>Conclusions</h4>Measurements of solid pulmonary nodule volume measured with standard-FBP were comparable with IR, regardless of the IR-level and no significant differences between measured volumes of both small and large solid nodules were found.
format	article
author	Martin J Willemink Jaap Borstlap Richard A P Takx Arnold M R Schilham Tim Leiner Ricardo P J Budde Pim A de Jong
author_facet	Martin J Willemink Jaap Borstlap Richard A P Takx Arnold M R Schilham Tim Leiner Ricardo P J Budde Pim A de Jong
author_sort	Martin J Willemink
title	The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
title_short	The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
title_full	The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
title_fullStr	The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
title_full_unstemmed	The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
title_sort	effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/0b1526671a9b4e379143ab519369b24d
work_keys_str_mv	AT martinjwillemink theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT jaapborstlap theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT richardaptakx theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT arnoldmrschilham theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT timleiner theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT ricardopjbudde theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT pimadejong theeffectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT martinjwillemink effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT jaapborstlap effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT richardaptakx effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT arnoldmrschilham effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT timleiner effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT ricardopjbudde effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification AT pimadejong effectsofcomputedtomographywithiterativereconstructiononsolidpulmonarynodulevolumequantification
_version_	1718422709657927680

The effects of computed tomography with iterative reconstruction on solid pulmonary nodule volume quantification.

Ejemplares similares