Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.

The embodied cognition hypothesis suggests that motor and premotor areas are automatically and necessarily involved in understanding action language, as word conceptual representations are embodied. This transcranial magnetic stimulation (TMS) study explores the role of the left primary motor cortex...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Liuba Papeo, Antonino Vallesi, Alessio Isaja, Raffaella Ida Rumiati
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0b1b9e496b364e33b0dbffbb6c00861a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0b1b9e496b364e33b0dbffbb6c00861a
record_format	dspace
spelling	oai:doaj.org-article:0b1b9e496b364e33b0dbffbb6c00861a2021-11-25T06:17:08ZEffects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.1932-620310.1371/journal.pone.0004508https://doaj.org/article/0b1b9e496b364e33b0dbffbb6c00861a2009-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19240793/?tool=EBIhttps://doaj.org/toc/1932-6203The embodied cognition hypothesis suggests that motor and premotor areas are automatically and necessarily involved in understanding action language, as word conceptual representations are embodied. This transcranial magnetic stimulation (TMS) study explores the role of the left primary motor cortex in action-verb processing. TMS-induced motor-evoked potentials from right-hand muscles were recorded as a measure of M1 activity, while participants were asked either to judge explicitly whether a verb was action-related (semantic task) or to decide on the number of syllables in a verb (syllabic task). TMS was applied in three different experiments at 170, 350 and 500 ms post-stimulus during both tasks to identify when the enhancement of M1 activity occurred during word processing. The delays between stimulus onset and magnetic stimulation were consistent with electrophysiological studies, suggesting that word recognition can be differentiated into early (within 200 ms) and late (within 400 ms) lexical-semantic stages, and post-conceptual stages. Reaction times and accuracy were recorded to measure the extent to which the participants' linguistic performance was affected by the interference of TMS with M1 activity. No enhancement of M1 activity specific for action verbs was found at 170 and 350 ms post-stimulus, when lexical-semantic processes are presumed to occur (Experiments 1-2). When TMS was applied at 500 ms post-stimulus (Experiment 3), processing action verbs, compared with non-action verbs, increased the M1-activity in the semantic task and decreased it in the syllabic task. This effect was specific for hand-action verbs and was not observed for action-verbs related to other body parts. Neither accuracy nor RTs were affected by TMS. These findings suggest that the lexical-semantic processing of action verbs does not automatically activate the M1. This area seems to be rather involved in post-conceptual processing that follows the retrieval of motor representations, its activity being modulated (facilitated or inhibited), in a top-down manner, by the specific demand of the task.Liuba PapeoAntonino VallesiAlessio IsajaRaffaella Ida RumiatiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 4, Iss 2, p e4508 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Liuba Papeo Antonino Vallesi Alessio Isaja Raffaella Ida Rumiati Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
description	The embodied cognition hypothesis suggests that motor and premotor areas are automatically and necessarily involved in understanding action language, as word conceptual representations are embodied. This transcranial magnetic stimulation (TMS) study explores the role of the left primary motor cortex in action-verb processing. TMS-induced motor-evoked potentials from right-hand muscles were recorded as a measure of M1 activity, while participants were asked either to judge explicitly whether a verb was action-related (semantic task) or to decide on the number of syllables in a verb (syllabic task). TMS was applied in three different experiments at 170, 350 and 500 ms post-stimulus during both tasks to identify when the enhancement of M1 activity occurred during word processing. The delays between stimulus onset and magnetic stimulation were consistent with electrophysiological studies, suggesting that word recognition can be differentiated into early (within 200 ms) and late (within 400 ms) lexical-semantic stages, and post-conceptual stages. Reaction times and accuracy were recorded to measure the extent to which the participants' linguistic performance was affected by the interference of TMS with M1 activity. No enhancement of M1 activity specific for action verbs was found at 170 and 350 ms post-stimulus, when lexical-semantic processes are presumed to occur (Experiments 1-2). When TMS was applied at 500 ms post-stimulus (Experiment 3), processing action verbs, compared with non-action verbs, increased the M1-activity in the semantic task and decreased it in the syllabic task. This effect was specific for hand-action verbs and was not observed for action-verbs related to other body parts. Neither accuracy nor RTs were affected by TMS. These findings suggest that the lexical-semantic processing of action verbs does not automatically activate the M1. This area seems to be rather involved in post-conceptual processing that follows the retrieval of motor representations, its activity being modulated (facilitated or inhibited), in a top-down manner, by the specific demand of the task.
format	article
author	Liuba Papeo Antonino Vallesi Alessio Isaja Raffaella Ida Rumiati
author_facet	Liuba Papeo Antonino Vallesi Alessio Isaja Raffaella Ida Rumiati
author_sort	Liuba Papeo
title	Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
title_short	Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
title_full	Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
title_fullStr	Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
title_full_unstemmed	Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.
title_sort	effects of tms on different stages of motor and non-motor verb processing in the primary motor cortex.
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/0b1b9e496b364e33b0dbffbb6c00861a
work_keys_str_mv	AT liubapapeo effectsoftmsondifferentstagesofmotorandnonmotorverbprocessingintheprimarymotorcortex AT antoninovallesi effectsoftmsondifferentstagesofmotorandnonmotorverbprocessingintheprimarymotorcortex AT alessioisaja effectsoftmsondifferentstagesofmotorandnonmotorverbprocessingintheprimarymotorcortex AT raffaellaidarumiati effectsoftmsondifferentstagesofmotorandnonmotorverbprocessingintheprimarymotorcortex
_version_	1718413965300596736

Effects of TMS on different stages of motor and non-motor verb processing in the primary motor cortex.

Ejemplares similares