Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.

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Detalles Bibliográficos
Autores principales: S. Dallari, M. Macal, M. E. Loureiro, Y. Jo, L. Swanson, C. Hesser, P. Ghosh, E. I. Zuniga
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a
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Descripción
Sumario:Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.