Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.

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Autores principales: S. Dallari, M. Macal, M. E. Loureiro, Y. Jo, L. Swanson, C. Hesser, P. Ghosh, E. I. Zuniga
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a
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spelling oai:doaj.org-article:0b1ba38c031e4c458b61acacfa80af6a2021-12-02T14:42:40ZSrc family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses10.1038/ncomms148302041-1723https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14830https://doaj.org/toc/2041-1723Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.S. DallariM. MacalM. E. LoureiroY. JoL. SwansonC. HesserP. GhoshE. I. ZunigaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. Dallari
M. Macal
M. E. Loureiro
Y. Jo
L. Swanson
C. Hesser
P. Ghosh
E. I. Zuniga
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
description Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.
format article
author S. Dallari
M. Macal
M. E. Loureiro
Y. Jo
L. Swanson
C. Hesser
P. Ghosh
E. I. Zuniga
author_facet S. Dallari
M. Macal
M. E. Loureiro
Y. Jo
L. Swanson
C. Hesser
P. Ghosh
E. I. Zuniga
author_sort S. Dallari
title Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
title_short Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
title_full Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
title_fullStr Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
title_full_unstemmed Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
title_sort src family kinases fyn and lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a
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