Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.
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Nature Portfolio
2017
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oai:doaj.org-article:0b1ba38c031e4c458b61acacfa80af6a2021-12-02T14:42:40ZSrc family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses10.1038/ncomms148302041-1723https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14830https://doaj.org/toc/2041-1723Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.S. DallariM. MacalM. E. LoureiroY. JoL. SwansonC. HesserP. GhoshE. I. ZunigaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
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Science Q S. Dallari M. Macal M. E. Loureiro Y. Jo L. Swanson C. Hesser P. Ghosh E. I. Zuniga Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
description |
Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs. |
format |
article |
author |
S. Dallari M. Macal M. E. Loureiro Y. Jo L. Swanson C. Hesser P. Ghosh E. I. Zuniga |
author_facet |
S. Dallari M. Macal M. E. Loureiro Y. Jo L. Swanson C. Hesser P. Ghosh E. I. Zuniga |
author_sort |
S. Dallari |
title |
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
title_short |
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
title_full |
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
title_fullStr |
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
title_full_unstemmed |
Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
title_sort |
src family kinases fyn and lyn are constitutively activated and mediate plasmacytoid dendritic cell responses |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a |
work_keys_str_mv |
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_version_ |
1718389611668963328 |