Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.

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Detalles Bibliográficos
Autores principales: S. Dallari, M. Macal, M. E. Loureiro, Y. Jo, L. Swanson, C. Hesser, P. Ghosh, E. I. Zuniga
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/0b1ba38c031e4c458b61acacfa80af6a
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