Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al. show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusi...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/0b20de240c044028a38062003767bd6c |
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| Sumario: | HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al. show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusion. |
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