Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion

HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al. show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusi...

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Autores principales: Sung-Tae Yang, Volker Kiessling, Lukas K. Tamm
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0b20de240c044028a38062003767bd6c
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spelling oai:doaj.org-article:0b20de240c044028a38062003767bd6c2021-12-02T15:34:53ZLine tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion10.1038/ncomms114012041-1723https://doaj.org/article/0b20de240c044028a38062003767bd6c2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11401https://doaj.org/toc/2041-1723HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al. show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusion.Sung-Tae YangVolker KiesslingLukas K. TammNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sung-Tae Yang
Volker Kiessling
Lukas K. Tamm
Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
description HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al. show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusion.
format article
author Sung-Tae Yang
Volker Kiessling
Lukas K. Tamm
author_facet Sung-Tae Yang
Volker Kiessling
Lukas K. Tamm
author_sort Sung-Tae Yang
title Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
title_short Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
title_full Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
title_fullStr Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
title_full_unstemmed Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
title_sort line tension at lipid phase boundaries as driving force for hiv fusion peptide-mediated fusion
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/0b20de240c044028a38062003767bd6c
work_keys_str_mv AT sungtaeyang linetensionatlipidphaseboundariesasdrivingforceforhivfusionpeptidemediatedfusion
AT volkerkiessling linetensionatlipidphaseboundariesasdrivingforceforhivfusionpeptidemediatedfusion
AT lukasktamm linetensionatlipidphaseboundariesasdrivingforceforhivfusionpeptidemediatedfusion
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