Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice.

The pathophysiological mechanisms of both familial and sporadic Amyotrophic Lateral Sclerosis (ALS) are unknown, although growing evidence suggests that skeletal muscle tissue is a primary target of ALS toxicity. Skeletal muscle biopsies were performed on transgenic SOD1(G93A) mice, a mouse model of...

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Main Authors: Ana C Calvo, Raquel Manzano, Gabriela Atencia-Cibreiro, Sara Oliván, María J Muñoz, Pilar Zaragoza, Pilar Cordero-Vázquez, Jesús Esteban-Pérez, Alberto García-Redondo, Rosario Osta
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/0b29545086dd470c8e4430df219cdfb0
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