Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with...
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oai:doaj.org-article:0b2a055f599c416a87bdb751e2791d4a2021-12-05T12:23:51ZUmbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report10.1186/s13256-021-03139-z1752-1947https://doaj.org/article/0b2a055f599c416a87bdb751e2791d4a2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13256-021-03139-zhttps://doaj.org/toc/1752-1947Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with severe progressive supranuclear palsy and treated with umbilical cord blood stem cells transplantation. After the umbilical cord blood stem cells therapy, his neurologic symptoms stopped deteriorating, his muscle rigidity was mildly improved, and he remains alive for more than 8 years. Conclusions Umbilical cord blood stem cells transplantation may be an alternative therapy for patients with severe progressive supranuclear palsy.Huiping LiFang YuanYaming DuTao PanWanxin WenShaoxue LiLixin WangAili LuBMCarticleProgressive supranuclear palsyUmbilical cord bloodStem cellsCase reportMedicineRENJournal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021) |
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Progressive supranuclear palsy Umbilical cord blood Stem cells Case report Medicine R |
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Progressive supranuclear palsy Umbilical cord blood Stem cells Case report Medicine R Huiping Li Fang Yuan Yaming Du Tao Pan Wanxin Wen Shaoxue Li Lixin Wang Aili Lu Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
description |
Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with severe progressive supranuclear palsy and treated with umbilical cord blood stem cells transplantation. After the umbilical cord blood stem cells therapy, his neurologic symptoms stopped deteriorating, his muscle rigidity was mildly improved, and he remains alive for more than 8 years. Conclusions Umbilical cord blood stem cells transplantation may be an alternative therapy for patients with severe progressive supranuclear palsy. |
format |
article |
author |
Huiping Li Fang Yuan Yaming Du Tao Pan Wanxin Wen Shaoxue Li Lixin Wang Aili Lu |
author_facet |
Huiping Li Fang Yuan Yaming Du Tao Pan Wanxin Wen Shaoxue Li Lixin Wang Aili Lu |
author_sort |
Huiping Li |
title |
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
title_short |
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
title_full |
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
title_fullStr |
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
title_full_unstemmed |
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
title_sort |
umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report |
publisher |
BMC |
publishDate |
2021 |
url |
https://doaj.org/article/0b2a055f599c416a87bdb751e2791d4a |
work_keys_str_mv |
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1718371940497883136 |