Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report

Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with...

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Autores principales: Huiping Li, Fang Yuan, Yaming Du, Tao Pan, Wanxin Wen, Shaoxue Li, Lixin Wang, Aili Lu
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/0b2a055f599c416a87bdb751e2791d4a
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spelling oai:doaj.org-article:0b2a055f599c416a87bdb751e2791d4a2021-12-05T12:23:51ZUmbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report10.1186/s13256-021-03139-z1752-1947https://doaj.org/article/0b2a055f599c416a87bdb751e2791d4a2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13256-021-03139-zhttps://doaj.org/toc/1752-1947Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with severe progressive supranuclear palsy and treated with umbilical cord blood stem cells transplantation. After the umbilical cord blood stem cells therapy, his neurologic symptoms stopped deteriorating, his muscle rigidity was mildly improved, and he remains alive for more than 8 years. Conclusions Umbilical cord blood stem cells transplantation may be an alternative therapy for patients with severe progressive supranuclear palsy.Huiping LiFang YuanYaming DuTao PanWanxin WenShaoxue LiLixin WangAili LuBMCarticleProgressive supranuclear palsyUmbilical cord bloodStem cellsCase reportMedicineRENJournal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Progressive supranuclear palsy
Umbilical cord blood
Stem cells
Case report
Medicine
R
spellingShingle Progressive supranuclear palsy
Umbilical cord blood
Stem cells
Case report
Medicine
R
Huiping Li
Fang Yuan
Yaming Du
Tao Pan
Wanxin Wen
Shaoxue Li
Lixin Wang
Aili Lu
Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
description Abstract Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy. Case presentation We present a case of a 61-year-old Chinese man with severe progressive supranuclear palsy and treated with umbilical cord blood stem cells transplantation. After the umbilical cord blood stem cells therapy, his neurologic symptoms stopped deteriorating, his muscle rigidity was mildly improved, and he remains alive for more than 8 years. Conclusions Umbilical cord blood stem cells transplantation may be an alternative therapy for patients with severe progressive supranuclear palsy.
format article
author Huiping Li
Fang Yuan
Yaming Du
Tao Pan
Wanxin Wen
Shaoxue Li
Lixin Wang
Aili Lu
author_facet Huiping Li
Fang Yuan
Yaming Du
Tao Pan
Wanxin Wen
Shaoxue Li
Lixin Wang
Aili Lu
author_sort Huiping Li
title Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
title_short Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
title_full Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
title_fullStr Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
title_full_unstemmed Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
title_sort umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report
publisher BMC
publishDate 2021
url https://doaj.org/article/0b2a055f599c416a87bdb751e2791d4a
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AT fangyuan umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT yamingdu umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT taopan umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT wanxinwen umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT shaoxueli umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT lixinwang umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
AT aililu umbilicalcordbloodstemcellstransplantationinapatientwithsevereprogressivesupranuclearpalsyacasereport
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