Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma
The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters of cells that may influence patient survival.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:0b2c6fcf4f674aa2b645939100155c52 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:0b2c6fcf4f674aa2b645939100155c522021-12-02T15:52:50ZComprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma10.1038/s41467-021-21795-z2041-1723https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c522021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21795-zhttps://doaj.org/toc/2041-1723The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters of cells that may influence patient survival.Lanqi GongDora Lai-Wan KwongWei DaiPingan WuShanshan LiQian YanYu ZhangBaifeng ZhangXiaona FangLi LiuMin LuoBeilei LiuLarry Ka-Yue ChowQingyun ChenJinlin HuangVictor Ho-Fun LeeKa-On LamAnthony Wing-Ip LoZhiwei ChenYan WangAnne Wing-Mui LeeXin-Yuan GuanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Lanqi Gong Dora Lai-Wan Kwong Wei Dai Pingan Wu Shanshan Li Qian Yan Yu Zhang Baifeng Zhang Xiaona Fang Li Liu Min Luo Beilei Liu Larry Ka-Yue Chow Qingyun Chen Jinlin Huang Victor Ho-Fun Lee Ka-On Lam Anthony Wing-Ip Lo Zhiwei Chen Yan Wang Anne Wing-Mui Lee Xin-Yuan Guan Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| description |
The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters of cells that may influence patient survival. |
| format |
article |
| author |
Lanqi Gong Dora Lai-Wan Kwong Wei Dai Pingan Wu Shanshan Li Qian Yan Yu Zhang Baifeng Zhang Xiaona Fang Li Liu Min Luo Beilei Liu Larry Ka-Yue Chow Qingyun Chen Jinlin Huang Victor Ho-Fun Lee Ka-On Lam Anthony Wing-Ip Lo Zhiwei Chen Yan Wang Anne Wing-Mui Lee Xin-Yuan Guan |
| author_facet |
Lanqi Gong Dora Lai-Wan Kwong Wei Dai Pingan Wu Shanshan Li Qian Yan Yu Zhang Baifeng Zhang Xiaona Fang Li Liu Min Luo Beilei Liu Larry Ka-Yue Chow Qingyun Chen Jinlin Huang Victor Ho-Fun Lee Ka-On Lam Anthony Wing-Ip Lo Zhiwei Chen Yan Wang Anne Wing-Mui Lee Xin-Yuan Guan |
| author_sort |
Lanqi Gong |
| title |
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| title_short |
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| title_full |
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| title_fullStr |
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| title_full_unstemmed |
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| title_sort |
comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52 |
| work_keys_str_mv |
AT lanqigong comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT doralaiwankwong comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT weidai comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT pinganwu comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT shanshanli comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT qianyan comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT yuzhang comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT baifengzhang comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT xiaonafang comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT liliu comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT minluo comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT beileiliu comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT larrykayuechow comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT qingyunchen comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT jinlinhuang comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT victorhofunlee comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT kaonlam comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT anthonywingiplo comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT zhiweichen comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT yanwang comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT annewingmuilee comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma AT xinyuanguan comprehensivesinglecellsequencingrevealsthestromaldynamicsandtumorspecificcharacteristicsinthemicroenvironmentofnasopharyngealcarcinoma |
| _version_ |
1718385553244684288 |