GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells
Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs).
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De Gruyter
2021
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oai:doaj.org-article:0b3e55f188ce46e6b8137b0d92111d592021-12-05T14:10:55ZGJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells2391-546310.1515/med-2021-0344https://doaj.org/article/0b3e55f188ce46e6b8137b0d92111d592021-09-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0344https://doaj.org/toc/2391-5463Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs).Niu GengmingZhang XiaotianHong RunqiYang XiminGu JiaweiSong TaoHu ZhiqingChen LiangWang XinXia JieKe ZhongweiRen JunHong LiangDe Gruyterarticlehepatocellular carcinomametastasishepatic stellate celltgf-βepithelial–mesenchymal transitionMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 1459-1471 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
hepatocellular carcinoma metastasis hepatic stellate cell tgf-β epithelial–mesenchymal transition Medicine R |
| spellingShingle |
hepatocellular carcinoma metastasis hepatic stellate cell tgf-β epithelial–mesenchymal transition Medicine R Niu Gengming Zhang Xiaotian Hong Runqi Yang Ximin Gu Jiawei Song Tao Hu Zhiqing Chen Liang Wang Xin Xia Jie Ke Zhongwei Ren Jun Hong Liang GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| description |
Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs). |
| format |
article |
| author |
Niu Gengming Zhang Xiaotian Hong Runqi Yang Ximin Gu Jiawei Song Tao Hu Zhiqing Chen Liang Wang Xin Xia Jie Ke Zhongwei Ren Jun Hong Liang |
| author_facet |
Niu Gengming Zhang Xiaotian Hong Runqi Yang Ximin Gu Jiawei Song Tao Hu Zhiqing Chen Liang Wang Xin Xia Jie Ke Zhongwei Ren Jun Hong Liang |
| author_sort |
Niu Gengming |
| title |
GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| title_short |
GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| title_full |
GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| title_fullStr |
GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| title_full_unstemmed |
GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| title_sort |
gja1 promotes hepatocellular carcinoma progression by mediating tgf-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells |
| publisher |
De Gruyter |
| publishDate |
2021 |
| url |
https://doaj.org/article/0b3e55f188ce46e6b8137b0d92111d59 |
| work_keys_str_mv |
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1718371582223581184 |