GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells

GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells

Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs).

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Detalles Bibliográficos
Autores principales: Niu Gengming, Zhang Xiaotian, Hong Runqi, Yang Ximin, Gu Jiawei, Song Tao, Hu Zhiqing, Chen Liang, Wang Xin, Xia Jie, Ke Zhongwei, Ren Jun, Hong Liang
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
Materias:
hepatocellular carcinoma
metastasis
hepatic stellate cell
tgf-β
epithelial–mesenchymal transition
Medicine
R
Acceso en línea:https://doaj.org/article/0b3e55f188ce46e6b8137b0d92111d59
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