Erectile dysfunction in men with diabetes (literature review). Part 2

The second part of review article highlights modern views on the diagnosis and treatment of erectile dysfunction (ED) in men with diabetes mellitus (DM). Google Scholar and PubMed databases were used to search for literature sources. The role of comorbid diseases in the development of ED in men with...

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Autores principales:	Е.V. Luchytskiy, V.E. Luchytskiy
Formato:	article
Lenguaje:	EN RU UK
Publicado:	Publishing House Zaslavsky 2021
Materias:	diabetes mellitus, man, erectile dysfunction, testosterone, phosphodiesterase type 5 inhibitors Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/0b3fbcd503af4039bf4cf227a5d38f64
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spelling	oai:doaj.org-article:0b3fbcd503af4039bf4cf227a5d38f642021-11-22T11:26:20ZErectile dysfunction in men with diabetes (literature review). Part 22224-07212307-142710.22141/2224-0721.17.6.2021.243218https://doaj.org/article/0b3fbcd503af4039bf4cf227a5d38f642021-10-01T00:00:00Zhttp://iej.zaslavsky.com.ua/article/view/243218https://doaj.org/toc/2224-0721https://doaj.org/toc/2307-1427The second part of review article highlights modern views on the diagnosis and treatment of erectile dysfunction (ED) in men with diabetes mellitus (DM). Google Scholar and PubMed databases were used to search for literature sources. The role of comorbid diseases in the development of ED in men with diabetes mellitus has been shown. The generalized data on the main clinical manifestations of erectile dysfunction, methods of its diagnosis and treatment are given. A number of epidemiological studies over the past 20 years have found that erectile dysfunction in men with diabetes may be an early marker of cardiovascular complications. Thus, in the algorithm for the diagnosis of ED in patients with diabetes it is necessary to conduct a thorough examination of the cardiovascular system. The article describes modern therapeutic and surgical methods of ED treatment. Numerous literature sources indicate an important role of the correction of androgen deficiency in men with type 2 diabetes to enhance the effectiveness of phosphodiesterase type 5 (PDE5) inhibitors. The literature review shows the data on the emergence of new PDE5 inhibitors, which have a higher selectivity compared to existing ones that provides a better therapeutic effect and reduces the frequency and severity of side effects. The modern algorithm for the treatment of ED in men involves the sequential stages of using different treatments. The last link of therapy, in case of inefficiency of the previous ones, is penile prosthesis. Implantation of three-piece penile prosthesis is an effective method of ED treatment. The use of this method in patients with severe forms of ED on the background of diabetes, in case of ineffectiveness of PDE5 inhibitors and intracavernous injections of vasoactive drugs, is considered promising.Е.V. LuchytskiyV.E. LuchytskiyPublishing House Zaslavskyarticlediabetes mellitus, man, erectile dysfunction, testosterone, phosphodiesterase type 5 inhibitorsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENRUUKMìžnarodnij Endokrinologìčnij Žurnal, Vol 17, Iss 6, Pp 513-519 (2021)
institution	DOAJ
collection	DOAJ
language	EN RU UK
topic	diabetes mellitus, man, erectile dysfunction, testosterone, phosphodiesterase type 5 inhibitors Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	diabetes mellitus, man, erectile dysfunction, testosterone, phosphodiesterase type 5 inhibitors Diseases of the endocrine glands. Clinical endocrinology RC648-665 Е.V. Luchytskiy V.E. Luchytskiy Erectile dysfunction in men with diabetes (literature review). Part 2
description	The second part of review article highlights modern views on the diagnosis and treatment of erectile dysfunction (ED) in men with diabetes mellitus (DM). Google Scholar and PubMed databases were used to search for literature sources. The role of comorbid diseases in the development of ED in men with diabetes mellitus has been shown. The generalized data on the main clinical manifestations of erectile dysfunction, methods of its diagnosis and treatment are given. A number of epidemiological studies over the past 20 years have found that erectile dysfunction in men with diabetes may be an early marker of cardiovascular complications. Thus, in the algorithm for the diagnosis of ED in patients with diabetes it is necessary to conduct a thorough examination of the cardiovascular system. The article describes modern therapeutic and surgical methods of ED treatment. Numerous literature sources indicate an important role of the correction of androgen deficiency in men with type 2 diabetes to enhance the effectiveness of phosphodiesterase type 5 (PDE5) inhibitors. The literature review shows the data on the emergence of new PDE5 inhibitors, which have a higher selectivity compared to existing ones that provides a better therapeutic effect and reduces the frequency and severity of side effects. The modern algorithm for the treatment of ED in men involves the sequential stages of using different treatments. The last link of therapy, in case of inefficiency of the previous ones, is penile prosthesis. Implantation of three-piece penile prosthesis is an effective method of ED treatment. The use of this method in patients with severe forms of ED on the background of diabetes, in case of ineffectiveness of PDE5 inhibitors and intracavernous injections of vasoactive drugs, is considered promising.
format	article
author	Е.V. Luchytskiy V.E. Luchytskiy
author_facet	Е.V. Luchytskiy V.E. Luchytskiy
author_sort	Е.V. Luchytskiy
title	Erectile dysfunction in men with diabetes (literature review). Part 2
title_short	Erectile dysfunction in men with diabetes (literature review). Part 2
title_full	Erectile dysfunction in men with diabetes (literature review). Part 2
title_fullStr	Erectile dysfunction in men with diabetes (literature review). Part 2
title_full_unstemmed	Erectile dysfunction in men with diabetes (literature review). Part 2
title_sort	erectile dysfunction in men with diabetes (literature review). part 2
publisher	Publishing House Zaslavsky
publishDate	2021
url	https://doaj.org/article/0b3fbcd503af4039bf4cf227a5d38f64
work_keys_str_mv	AT evluchytskiy erectiledysfunctioninmenwithdiabetesliteraturereviewpart2 AT veluchytskiy erectiledysfunctioninmenwithdiabetesliteraturereviewpart2
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Erectile dysfunction in men with diabetes (literature review). Part 2

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