Recapitulation of HDV infection in a fully permissive hepatoma cell line allows efficient drug evaluation
Hepatitis delta virus (HDV) depends on the envelope proteins of hepatitis B virus (HBV) for virion production. Here, Lempp et al. produce a cell line expressing HBV envelope proteins and their receptor, which allows continuous secretion of infectious progeny HDV and testing of antiviral drugs.
Guardado en:
Autores principales: | Florian A. Lempp, Franziska Schlund, Lisa Rieble, Lea Nussbaum, Corinna Link, Zhenfeng Zhang, Yi Ni, Stephan Urban |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/0b4c7b835d4c4558b301caf070bd4e81 |
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