Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract

Abstract. Walean M, Melpin R, Rondonuwu M, Pinontoan KF, Maliangkay HP, Astriani M. 2020. Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract. Biodiversitas 21: 2377-2382. Pakoba (Syzygium luzonense (Merr.) Merr) as an endemic and ethnomedical p...

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Autores principales:	Mario Walean, ROSTINA MELPIN, MERVINA RONDONUWU, KINZIE FELICIANO PINONTOAN, Hendra Pratama Maliangkay, MELI ASTRIANI
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	antibacterial, antihyperglycemic, antioxidant, bioactivities, pakoba, syzygium luzonense Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0b4d0a1537924ee6b59a10907217acd1
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spelling	oai:doaj.org-article:0b4d0a1537924ee6b59a10907217acd12021-11-22T00:40:46ZPhytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract1412-033X2085-472210.13057/biodiv/d210606https://doaj.org/article/0b4d0a1537924ee6b59a10907217acd12020-05-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5712https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Walean M, Melpin R, Rondonuwu M, Pinontoan KF, Maliangkay HP, Astriani M. 2020. Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract. Biodiversitas 21: 2377-2382. Pakoba (Syzygium luzonense (Merr.) Merr) as an endemic and ethnomedical plant of North Sulawesi was investigated for its phytochemical constituents and biological activities. The presence of phytochemicals constituents, antibacterial, antioxidant activities, and antihyperglycemic of pakoba stem bark ethanolic extract (PSBEE) were also investigated. Pakoba stem bark was extracted using ethanol. The extracts were evaluated for antimicrobial activity using the Kirby Bauer method, whereas antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay. Alloxan-induced diabetic rats investigation was used to determine the antihyperglycemic activity. The phytochemical analysis revealed that tannins, alkaloids, and flavonoids were present in PSBEE. PSBEE has potent antioxidant activity with antioxidant activity index = 1.02. PSBEE significantly reduced the blood sugar of hyperglycemic rats with an optimum dose of 300 mg/kgbw. In this study, PSBEE has weak antibacterial activity against in Escherichia coli and Staphylococcus aureus.Mario WaleanROSTINA MELPINMERVINA RONDONUWUKINZIE FELICIANO PINONTOANHendra Pratama MaliangkayMELI ASTRIANIMBI & UNS Soloarticleantibacterial, antihyperglycemic, antioxidant, bioactivities, pakoba, syzygium luzonenseBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	antibacterial, antihyperglycemic, antioxidant, bioactivities, pakoba, syzygium luzonense Biology (General) QH301-705.5
spellingShingle	antibacterial, antihyperglycemic, antioxidant, bioactivities, pakoba, syzygium luzonense Biology (General) QH301-705.5 Mario Walean ROSTINA MELPIN MERVINA RONDONUWU KINZIE FELICIANO PINONTOAN Hendra Pratama Maliangkay MELI ASTRIANI Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
description	Abstract. Walean M, Melpin R, Rondonuwu M, Pinontoan KF, Maliangkay HP, Astriani M. 2020. Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract. Biodiversitas 21: 2377-2382. Pakoba (Syzygium luzonense (Merr.) Merr) as an endemic and ethnomedical plant of North Sulawesi was investigated for its phytochemical constituents and biological activities. The presence of phytochemicals constituents, antibacterial, antioxidant activities, and antihyperglycemic of pakoba stem bark ethanolic extract (PSBEE) were also investigated. Pakoba stem bark was extracted using ethanol. The extracts were evaluated for antimicrobial activity using the Kirby Bauer method, whereas antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay. Alloxan-induced diabetic rats investigation was used to determine the antihyperglycemic activity. The phytochemical analysis revealed that tannins, alkaloids, and flavonoids were present in PSBEE. PSBEE has potent antioxidant activity with antioxidant activity index = 1.02. PSBEE significantly reduced the blood sugar of hyperglycemic rats with an optimum dose of 300 mg/kgbw. In this study, PSBEE has weak antibacterial activity against in Escherichia coli and Staphylococcus aureus.
format	article
author	Mario Walean ROSTINA MELPIN MERVINA RONDONUWU KINZIE FELICIANO PINONTOAN Hendra Pratama Maliangkay MELI ASTRIANI
author_facet	Mario Walean ROSTINA MELPIN MERVINA RONDONUWU KINZIE FELICIANO PINONTOAN Hendra Pratama Maliangkay MELI ASTRIANI
author_sort	Mario Walean
title	Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
title_short	Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
title_full	Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
title_fullStr	Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
title_full_unstemmed	Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract
title_sort	phytochemical screening and biological activities of pakoba (syzygium luzonense) stem bark ethanol extract
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/0b4d0a1537924ee6b59a10907217acd1
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Phytochemical screening and biological activities of pakoba (Syzygium luzonense) stem bark ethanol extract

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