Synthetic route optimization of Sumepirin antiepileptic drug candidate

In this work we describe the transformation of synthetic route of the antiepileptic drug candidate Sumepirin starting from discovery stage. Initial method included six step process requiring two steps of purification using colon chromatography and has poor overall yield of target compound. The proce...

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Autores principales: M. S. Dzyurkevich, N. V. Shtyrlin, Y. G. Shtyrlin
Formato: article
Lenguaje:EN
RU
Publicado: Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina 2020
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Acceso en línea:https://doaj.org/article/0b4d80d52c6f45078fe7ada733d90e04
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