A viral genome packaging ring-ATPase is a flexibly coordinated pentamer

In viruses, multi-subunit ring-ATPases are involved in genome packaging. Here, using single-molecule techniques, the authors determine that the active bacteriophage T4 DNA packaging motor is a pentamer and show that the motor can tolerate inactive subunits, suggesting that strict coordination betwee...

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Autores principales:	Li Dai, Digvijay Singh, Suoang Lu, Vishal I. Kottadiel, Reza Vafabakhsh, Marthandan Mahalingam, Yann R. Chemla, Taekjip Ha, Venigalla B. Rao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0b529d51539e44cd8a86334c5969b133
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spelling	oai:doaj.org-article:0b529d51539e44cd8a86334c5969b1332021-11-14T12:36:06ZA viral genome packaging ring-ATPase is a flexibly coordinated pentamer10.1038/s41467-021-26800-z2041-1723https://doaj.org/article/0b529d51539e44cd8a86334c5969b1332021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26800-zhttps://doaj.org/toc/2041-1723In viruses, multi-subunit ring-ATPases are involved in genome packaging. Here, using single-molecule techniques, the authors determine that the active bacteriophage T4 DNA packaging motor is a pentamer and show that the motor can tolerate inactive subunits, suggesting that strict coordination between the subunits is not crucial.Li DaiDigvijay SinghSuoang LuVishal I. KottadielReza VafabakhshMarthandan MahalingamYann R. ChemlaTaekjip HaVenigalla B. RaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Li Dai Digvijay Singh Suoang Lu Vishal I. Kottadiel Reza Vafabakhsh Marthandan Mahalingam Yann R. Chemla Taekjip Ha Venigalla B. Rao A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
description	In viruses, multi-subunit ring-ATPases are involved in genome packaging. Here, using single-molecule techniques, the authors determine that the active bacteriophage T4 DNA packaging motor is a pentamer and show that the motor can tolerate inactive subunits, suggesting that strict coordination between the subunits is not crucial.
format	article
author	Li Dai Digvijay Singh Suoang Lu Vishal I. Kottadiel Reza Vafabakhsh Marthandan Mahalingam Yann R. Chemla Taekjip Ha Venigalla B. Rao
author_facet	Li Dai Digvijay Singh Suoang Lu Vishal I. Kottadiel Reza Vafabakhsh Marthandan Mahalingam Yann R. Chemla Taekjip Ha Venigalla B. Rao
author_sort	Li Dai
title	A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
title_short	A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
title_full	A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
title_fullStr	A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
title_full_unstemmed	A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
title_sort	viral genome packaging ring-atpase is a flexibly coordinated pentamer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0b529d51539e44cd8a86334c5969b133
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A viral genome packaging ring-ATPase is a flexibly coordinated pentamer

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