Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2
Abstract Cleavage and dissociation of a large N-terminal fragment and the consequent unmasking of a short sequence (Stachel) remaining on the N-terminus have been proposed as mechanisms of activation of some members of the adhesion G protein-coupled receptor (aGPCR) family. However, the identity of...
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Autores principales: | Abanoub A. Gad, Pedram Azimzadeh, Nariman Balenga |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/0b5f1f83714c4759b7b5a2d286ab6750 |
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