Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2

Abstract Cleavage and dissociation of a large N-terminal fragment and the consequent unmasking of a short sequence (Stachel) remaining on the N-terminus have been proposed as mechanisms of activation of some members of the adhesion G protein-coupled receptor (aGPCR) family. However, the identity of...

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Auteurs principaux: Abanoub A. Gad, Pedram Azimzadeh, Nariman Balenga
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/0b5f1f83714c4759b7b5a2d286ab6750
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