Characterising the mechanism of airway smooth muscle β2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells.

Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β2 agonist therapy. Using an in vitro model of RV infection, we investigated the mechanisms underlying RV-induced β2 adrenoceptor desensitization in p...

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Autores principales: David Van Ly, Alen Faiz, Christine Jenkins, Ben Crossett, Judith L Black, Brent McParland, Janette K Burgess, Brian G G Oliver
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/0b7931eb10c44f7d82117f181d73dadd
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