Rats spontaneously perceive global motion direction of drifting plaids.

Computing global motion direction of extended visual objects is a hallmark of primate high-level vision. Although neurons selective for global motion have also been found in mouse visual cortex, it remains unknown whether rodents can combine multiple motion signals into global, integrated percepts....

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Autores principales:	Giulio Matteucci, Benedetta Zattera, Rosilari Bellacosa Marotti, Davide Zoccolan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0b84d73219f0465880db96c2331f49d4
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spelling	oai:doaj.org-article:0b84d73219f0465880db96c2331f49d42021-12-02T19:57:48ZRats spontaneously perceive global motion direction of drifting plaids.1553-734X1553-735810.1371/journal.pcbi.1009415https://doaj.org/article/0b84d73219f0465880db96c2331f49d42021-09-01T00:00:00Zhttps://doi.org/10.1371/journal.pcbi.1009415https://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358Computing global motion direction of extended visual objects is a hallmark of primate high-level vision. Although neurons selective for global motion have also been found in mouse visual cortex, it remains unknown whether rodents can combine multiple motion signals into global, integrated percepts. To address this question, we trained two groups of rats to discriminate either gratings (G group) or plaids (i.e., superpositions of gratings with different orientations; P group) drifting horizontally along opposite directions. After the animals learned the task, we applied a visual priming paradigm, where presentation of the target stimulus was preceded by the brief presentation of either a grating or a plaid. The extent to which rat responses to the targets were biased by such prime stimuli provided a measure of the spontaneous, perceived similarity between primes and targets. We found that gratings and plaids, when used as primes, were equally effective at biasing the perception of plaid direction for the rats of the P group. Conversely, for the G group, only the gratings acted as effective prime stimuli, while the plaids failed to alter the perception of grating direction. To interpret these observations, we simulated a decision neuron reading out the representations of gratings and plaids, as conveyed by populations of either component or pattern cells (i.e., local or global motion detectors). We concluded that the findings for the P group are highly consistent with the existence of a population of pattern cells, playing a functional role similar to that demonstrated in primates. We also explored different scenarios that could explain the failure of the plaid stimuli to elicit a sizable priming magnitude for the G group. These simulations yielded testable predictions about the properties of motion representations in rodent visual cortex at the single-cell and circuitry level, thus paving the way to future neurophysiology experiments.Giulio MatteucciBenedetta ZatteraRosilari Bellacosa MarottiDavide ZoccolanPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 17, Iss 9, p e1009415 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Giulio Matteucci Benedetta Zattera Rosilari Bellacosa Marotti Davide Zoccolan Rats spontaneously perceive global motion direction of drifting plaids.
description	Computing global motion direction of extended visual objects is a hallmark of primate high-level vision. Although neurons selective for global motion have also been found in mouse visual cortex, it remains unknown whether rodents can combine multiple motion signals into global, integrated percepts. To address this question, we trained two groups of rats to discriminate either gratings (G group) or plaids (i.e., superpositions of gratings with different orientations; P group) drifting horizontally along opposite directions. After the animals learned the task, we applied a visual priming paradigm, where presentation of the target stimulus was preceded by the brief presentation of either a grating or a plaid. The extent to which rat responses to the targets were biased by such prime stimuli provided a measure of the spontaneous, perceived similarity between primes and targets. We found that gratings and plaids, when used as primes, were equally effective at biasing the perception of plaid direction for the rats of the P group. Conversely, for the G group, only the gratings acted as effective prime stimuli, while the plaids failed to alter the perception of grating direction. To interpret these observations, we simulated a decision neuron reading out the representations of gratings and plaids, as conveyed by populations of either component or pattern cells (i.e., local or global motion detectors). We concluded that the findings for the P group are highly consistent with the existence of a population of pattern cells, playing a functional role similar to that demonstrated in primates. We also explored different scenarios that could explain the failure of the plaid stimuli to elicit a sizable priming magnitude for the G group. These simulations yielded testable predictions about the properties of motion representations in rodent visual cortex at the single-cell and circuitry level, thus paving the way to future neurophysiology experiments.
format	article
author	Giulio Matteucci Benedetta Zattera Rosilari Bellacosa Marotti Davide Zoccolan
author_facet	Giulio Matteucci Benedetta Zattera Rosilari Bellacosa Marotti Davide Zoccolan
author_sort	Giulio Matteucci
title	Rats spontaneously perceive global motion direction of drifting plaids.
title_short	Rats spontaneously perceive global motion direction of drifting plaids.
title_full	Rats spontaneously perceive global motion direction of drifting plaids.
title_fullStr	Rats spontaneously perceive global motion direction of drifting plaids.
title_full_unstemmed	Rats spontaneously perceive global motion direction of drifting plaids.
title_sort	rats spontaneously perceive global motion direction of drifting plaids.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/0b84d73219f0465880db96c2331f49d4
work_keys_str_mv	AT giuliomatteucci ratsspontaneouslyperceiveglobalmotiondirectionofdriftingplaids AT benedettazattera ratsspontaneouslyperceiveglobalmotiondirectionofdriftingplaids AT rosilaribellacosamarotti ratsspontaneouslyperceiveglobalmotiondirectionofdriftingplaids AT davidezoccolan ratsspontaneouslyperceiveglobalmotiondirectionofdriftingplaids
_version_	1718375763533627392

Rats spontaneously perceive global motion direction of drifting plaids.

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