Interactive analysis of single-cell epigenomic landscapes with ChromSCape

Bulk approaches fail to capture the cell-to-cell heterogeneity of chromatin landscapes, while single-cell approaches provide low coverage datasets. Here, the authors present ChromSCape, a user-friendly interactive application that processes single-cell epigenomic data to assist the biological interp...

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Autores principales:	Pacôme Prompsy, Pia Kirchmeier, Justine Marsolier, Marc Deloger, Nicolas Servant, Céline Vallot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0b906fb8cdfb44efb7ca71d60a8115fd
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spelling	oai:doaj.org-article:0b906fb8cdfb44efb7ca71d60a8115fd2021-12-02T15:34:35ZInteractive analysis of single-cell epigenomic landscapes with ChromSCape10.1038/s41467-020-19542-x2041-1723https://doaj.org/article/0b906fb8cdfb44efb7ca71d60a8115fd2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19542-xhttps://doaj.org/toc/2041-1723Bulk approaches fail to capture the cell-to-cell heterogeneity of chromatin landscapes, while single-cell approaches provide low coverage datasets. Here, the authors present ChromSCape, a user-friendly interactive application that processes single-cell epigenomic data to assist the biological interpretation of chromatin landscapes within cell populations, as demonstrated in the context of cancer.Pacôme PrompsyPia KirchmeierJustine MarsolierMarc DelogerNicolas ServantCéline VallotNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pacôme Prompsy Pia Kirchmeier Justine Marsolier Marc Deloger Nicolas Servant Céline Vallot Interactive analysis of single-cell epigenomic landscapes with ChromSCape
description	Bulk approaches fail to capture the cell-to-cell heterogeneity of chromatin landscapes, while single-cell approaches provide low coverage datasets. Here, the authors present ChromSCape, a user-friendly interactive application that processes single-cell epigenomic data to assist the biological interpretation of chromatin landscapes within cell populations, as demonstrated in the context of cancer.
format	article
author	Pacôme Prompsy Pia Kirchmeier Justine Marsolier Marc Deloger Nicolas Servant Céline Vallot
author_facet	Pacôme Prompsy Pia Kirchmeier Justine Marsolier Marc Deloger Nicolas Servant Céline Vallot
author_sort	Pacôme Prompsy
title	Interactive analysis of single-cell epigenomic landscapes with ChromSCape
title_short	Interactive analysis of single-cell epigenomic landscapes with ChromSCape
title_full	Interactive analysis of single-cell epigenomic landscapes with ChromSCape
title_fullStr	Interactive analysis of single-cell epigenomic landscapes with ChromSCape
title_full_unstemmed	Interactive analysis of single-cell epigenomic landscapes with ChromSCape
title_sort	interactive analysis of single-cell epigenomic landscapes with chromscape
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0b906fb8cdfb44efb7ca71d60a8115fd
work_keys_str_mv	AT pacomeprompsy interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape AT piakirchmeier interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape AT justinemarsolier interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape AT marcdeloger interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape AT nicolasservant interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape AT celinevallot interactiveanalysisofsinglecellepigenomiclandscapeswithchromscape
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Interactive analysis of single-cell epigenomic landscapes with ChromSCape

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