Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish
The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-like embryonic cells during early morphogenesis.
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Nature Portfolio
2017
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oai:doaj.org-article:0b9b87f39cac4dc8b802f17c1ba4259f2021-12-02T14:42:03ZExtra-embryonic tissue spreading directs early embryo morphogenesis in killifish10.1038/ncomms154312041-1723https://doaj.org/article/0b9b87f39cac4dc8b802f17c1ba4259f2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15431https://doaj.org/toc/2041-1723The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-like embryonic cells during early morphogenesis.Germán ReigMauricio CerdaNéstor SepúlvedaDaniela FloresVictor CastañedaMasazumi TadaSteffen HärtelMiguel L. ConchaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Germán Reig Mauricio Cerda Néstor Sepúlveda Daniela Flores Victor Castañeda Masazumi Tada Steffen Härtel Miguel L. Concha Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
description |
The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-like embryonic cells during early morphogenesis. |
format |
article |
author |
Germán Reig Mauricio Cerda Néstor Sepúlveda Daniela Flores Victor Castañeda Masazumi Tada Steffen Härtel Miguel L. Concha |
author_facet |
Germán Reig Mauricio Cerda Néstor Sepúlveda Daniela Flores Victor Castañeda Masazumi Tada Steffen Härtel Miguel L. Concha |
author_sort |
Germán Reig |
title |
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
title_short |
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
title_full |
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
title_fullStr |
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
title_full_unstemmed |
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
title_sort |
extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/0b9b87f39cac4dc8b802f17c1ba4259f |
work_keys_str_mv |
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1718389792903790592 |