Theaflavin Chemistry and Its Health Benefits

Huge epidemiological and clinical studies have confirmed that black tea is a rich source of health-promoting ingredients, such as catechins and theaflavins (TFs). Furthermore, TF derivatives mainly include theaflavin (TF1), theaflavin-3-gallate (TF2A), theaflavin-3′-gallate (TF2B), and theaflavin-3,...

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Autores principales: Zhiguo Shan, Muhammad Farrukh Nisar, Mingxi Li, Chunhua Zhang, Chunpeng (Craig) Wan
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/0b9df961f403493294b18614a09e0bf8
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spelling oai:doaj.org-article:0b9df961f403493294b18614a09e0bf82021-11-29T00:56:06ZTheaflavin Chemistry and Its Health Benefits1942-099410.1155/2021/6256618https://doaj.org/article/0b9df961f403493294b18614a09e0bf82021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6256618https://doaj.org/toc/1942-0994Huge epidemiological and clinical studies have confirmed that black tea is a rich source of health-promoting ingredients, such as catechins and theaflavins (TFs). Furthermore, TF derivatives mainly include theaflavin (TF1), theaflavin-3-gallate (TF2A), theaflavin-3′-gallate (TF2B), and theaflavin-3,3′-digallate (TF3). All of these TFs exhibit extensive usages in pharmaceutics, foods, and traditional medication systems. Various indepth studies reported that how TFs modulates health effects in cellular and molecular mechanisms. The available literature regarding the pharmacological activities of TFs has revealed that TF3 has remarkable anti-inflammatory, antioxidant, anticancer, antiobesity, antiosteoporotic, and antimicrobial properties, thus posing significant effects on human health. The current manuscript summarizes both the chemistry and various pharmacological effects of TFs on human health, lifestyle or aging associated diseases, and populations of gut microbiota. Furthermore, the biological potential of TFs has also been focused to provide a deeper understanding of its mechanism of action.Zhiguo ShanMuhammad Farrukh NisarMingxi LiChunhua ZhangChunpeng (Craig) WanHindawi LimitedarticleCytologyQH573-671ENOxidative Medicine and Cellular Longevity, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Cytology
QH573-671
spellingShingle Cytology
QH573-671
Zhiguo Shan
Muhammad Farrukh Nisar
Mingxi Li
Chunhua Zhang
Chunpeng (Craig) Wan
Theaflavin Chemistry and Its Health Benefits
description Huge epidemiological and clinical studies have confirmed that black tea is a rich source of health-promoting ingredients, such as catechins and theaflavins (TFs). Furthermore, TF derivatives mainly include theaflavin (TF1), theaflavin-3-gallate (TF2A), theaflavin-3′-gallate (TF2B), and theaflavin-3,3′-digallate (TF3). All of these TFs exhibit extensive usages in pharmaceutics, foods, and traditional medication systems. Various indepth studies reported that how TFs modulates health effects in cellular and molecular mechanisms. The available literature regarding the pharmacological activities of TFs has revealed that TF3 has remarkable anti-inflammatory, antioxidant, anticancer, antiobesity, antiosteoporotic, and antimicrobial properties, thus posing significant effects on human health. The current manuscript summarizes both the chemistry and various pharmacological effects of TFs on human health, lifestyle or aging associated diseases, and populations of gut microbiota. Furthermore, the biological potential of TFs has also been focused to provide a deeper understanding of its mechanism of action.
format article
author Zhiguo Shan
Muhammad Farrukh Nisar
Mingxi Li
Chunhua Zhang
Chunpeng (Craig) Wan
author_facet Zhiguo Shan
Muhammad Farrukh Nisar
Mingxi Li
Chunhua Zhang
Chunpeng (Craig) Wan
author_sort Zhiguo Shan
title Theaflavin Chemistry and Its Health Benefits
title_short Theaflavin Chemistry and Its Health Benefits
title_full Theaflavin Chemistry and Its Health Benefits
title_fullStr Theaflavin Chemistry and Its Health Benefits
title_full_unstemmed Theaflavin Chemistry and Its Health Benefits
title_sort theaflavin chemistry and its health benefits
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/0b9df961f403493294b18614a09e0bf8
work_keys_str_mv AT zhiguoshan theaflavinchemistryanditshealthbenefits
AT muhammadfarrukhnisar theaflavinchemistryanditshealthbenefits
AT mingxili theaflavinchemistryanditshealthbenefits
AT chunhuazhang theaflavinchemistryanditshealthbenefits
AT chunpengcraigwan theaflavinchemistryanditshealthbenefits
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