CTL-mediated immunotherapy can suppress SHIV rebound in ART-free macaques

Viral rebound following discontinuation of antiretroviral therapy (ART) is a major obstacle for HIV cure. Here, the authors show that adoptive cellular therapy using autologous Env-specific T cells augmented by therapeutic vaccination can control viral rebound after ART interruption in a SHIV macaqu...

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Auteurs principaux: Jin Fan, Hua Liang, Xiaolin Ji, Shuo Wang, Jing Xue, Dan Li, Hong Peng, Chuan Qin, Cassian Yee, Yiming Shao
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
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Accès en ligne:https://doaj.org/article/0ba168e5395147c58ff5014f91356684
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