Structure of the human sodium leak channel NALCN in complex with FAM155A

Structure of the human sodium leak channel NALCN in complex with FAM155A

NALCN, a sodium leak channel, plays a key role in regulating the resting membrane potential and controlling neuronal excitability. Here the authors report a cryo-EM structure of human NALCN in complex with FAM155A, that with complementary functional analyses provide insights on its ion selectivity,...

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Autores principales: Jiongfang Xie, Meng Ke, Lizhen Xu, Shiyi Lin, Jin Huang, Jiabei Zhang, Fan Yang, Jianping Wu, Zhen Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/0ba8b9ca7116497c9d93aa32440a97ed
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