The Response Regulator BfmR Is a Potential Drug Target for <named-content content-type="genus-species">Acinetobacter baumannii</named-content>

The Response Regulator BfmR Is a Potential Drug Target for <named-content content-type="genus-species">Acinetobacter baumannii</named-content>

ABSTRACT Identification and validation is the first phase of target-based antimicrobial development. BfmR (RstA), a response regulator in a two-component signal transduction system (TCS) in Acinetobacter baumannii, is an intriguing potential antimicrobial target. A unique characteristic of BfmR is t...

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Autores principales: Thomas A. Russo, Akshay Manohar, Janet M. Beanan, Ruth Olson, Ulrike MacDonald, Jessica Graham, Timothy C. Umland
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Acinetobacter baumannii
Gram-negative bacilli
antibiotic target
bacterial drug target
drug discovery
essential genes
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/0bbb530e852f461ea2681f39154ed515
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