Structure and dynamics of the ASB9 CUL-RING E3 Ligase
Multi-subunit Cullin (CUL)-RING ligases (CRL) form the largest family of E3 ligases and are composed of a substrate receptor, a CUL, and a RING-box (RBX) protein. Here, the authors use cryo-EM and HDX-MS to characterise the ASB9 CUL-RING E3 ligase and present the structure of ASB9-ELOB/C bound to th...
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Autores principales: | Ryan J. Lumpkin, Richard W. Baker, Andres E. Leschziner, Elizabeth A. Komives |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/0bbb6cb9e2c74688aa91f0f7c786a41f |
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