IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS

Abstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-pl...

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Autores principales: V. A. Shcherbak, Yu. A. Vitkovsky, B. I. Kuznik
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/0bc181d3cd9e44058f90295754b0057d
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spelling oai:doaj.org-article:0bc181d3cd9e44058f90295754b0057d2021-11-18T08:03:37ZIMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS1563-06252313-741X10.15789/1563-0625-2008-1-59-66https://doaj.org/article/0bc181d3cd9e44058f90295754b0057d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/81https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-platelet adhesions were established. An increase of IL-1β, IL-2, TNFα and IFNα concentration was registered in absence of IL-4 changes. Application of thymaline, vilon and ventramine essentially improves clinical course of disease, results in normalization of immune profile, reduced levels of proimflammatory cytokines, restoration of lymphocyte-platelet adhesions.V. A. ShcherbakYu. A. VitkovskyB. I. KuznikSPb RAACIarticlechildrengastroduodenitisimmunitycytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 1, Pp 59-66 (2014)
institution DOAJ
collection DOAJ
language RU
topic children
gastroduodenitis
immunity
cytokines
Immunologic diseases. Allergy
RC581-607
spellingShingle children
gastroduodenitis
immunity
cytokines
Immunologic diseases. Allergy
RC581-607
V. A. Shcherbak
Yu. A. Vitkovsky
B. I. Kuznik
IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
description Abstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-platelet adhesions were established. An increase of IL-1β, IL-2, TNFα and IFNα concentration was registered in absence of IL-4 changes. Application of thymaline, vilon and ventramine essentially improves clinical course of disease, results in normalization of immune profile, reduced levels of proimflammatory cytokines, restoration of lymphocyte-platelet adhesions.
format article
author V. A. Shcherbak
Yu. A. Vitkovsky
B. I. Kuznik
author_facet V. A. Shcherbak
Yu. A. Vitkovsky
B. I. Kuznik
author_sort V. A. Shcherbak
title IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
title_short IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
title_full IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
title_fullStr IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
title_full_unstemmed IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
title_sort immune disturbances and substantiation of their correction in the children with chronic gastroduodenitis
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/0bc181d3cd9e44058f90295754b0057d
work_keys_str_mv AT vashcherbak immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis
AT yuavitkovsky immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis
AT bikuznik immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis
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