A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.

Guardado en:
Detalles Bibliográficos
Autores principales: Aubin Michalon, Andreas Hagenbuch, Christian Huy, Evita Varela, Benoit Combaluzier, Thibaud Damy, Ole B. Suhr, Maria J. Saraiva, Christoph Hock, Roger M. Nitsch, Jan Grimm
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/0bd15e092d1f47498ea907338e89a448
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:0bd15e092d1f47498ea907338e89a448
record_format dspace
spelling oai:doaj.org-article:0bd15e092d1f47498ea907338e89a4482021-12-02T16:52:58ZA human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells10.1038/s41467-021-23274-x2041-1723https://doaj.org/article/0bd15e092d1f47498ea907338e89a4482021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23274-xhttps://doaj.org/toc/2041-1723Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.Aubin MichalonAndreas HagenbuchChristian HuyEvita VarelaBenoit CombaluzierThibaud DamyOle B. SuhrMaria J. SaraivaChristoph HockRoger M. NitschJan GrimmNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aubin Michalon
Andreas Hagenbuch
Christian Huy
Evita Varela
Benoit Combaluzier
Thibaud Damy
Ole B. Suhr
Maria J. Saraiva
Christoph Hock
Roger M. Nitsch
Jan Grimm
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
description Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.
format article
author Aubin Michalon
Andreas Hagenbuch
Christian Huy
Evita Varela
Benoit Combaluzier
Thibaud Damy
Ole B. Suhr
Maria J. Saraiva
Christoph Hock
Roger M. Nitsch
Jan Grimm
author_facet Aubin Michalon
Andreas Hagenbuch
Christian Huy
Evita Varela
Benoit Combaluzier
Thibaud Damy
Ole B. Suhr
Maria J. Saraiva
Christoph Hock
Roger M. Nitsch
Jan Grimm
author_sort Aubin Michalon
title A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
title_short A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
title_full A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
title_fullStr A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
title_full_unstemmed A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
title_sort human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0bd15e092d1f47498ea907338e89a448
work_keys_str_mv AT aubinmichalon ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT andreashagenbuch ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT christianhuy ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT evitavarela ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT benoitcombaluzier ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT thibauddamy ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT olebsuhr ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT mariajsaraiva ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT christophhock ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT rogermnitsch ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT jangrimm ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT aubinmichalon humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT andreashagenbuch humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT christianhuy humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT evitavarela humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT benoitcombaluzier humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT thibauddamy humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT olebsuhr humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT mariajsaraiva humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT christophhock humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT rogermnitsch humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
AT jangrimm humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells
_version_ 1718382900995424256