A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells
Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0bd15e092d1f47498ea907338e89a448 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0bd15e092d1f47498ea907338e89a448 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0bd15e092d1f47498ea907338e89a4482021-12-02T16:52:58ZA human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells10.1038/s41467-021-23274-x2041-1723https://doaj.org/article/0bd15e092d1f47498ea907338e89a4482021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23274-xhttps://doaj.org/toc/2041-1723Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.Aubin MichalonAndreas HagenbuchChristian HuyEvita VarelaBenoit CombaluzierThibaud DamyOle B. SuhrMaria J. SaraivaChristoph HockRoger M. NitschJan GrimmNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Aubin Michalon Andreas Hagenbuch Christian Huy Evita Varela Benoit Combaluzier Thibaud Damy Ole B. Suhr Maria J. Saraiva Christoph Hock Roger M. Nitsch Jan Grimm A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
description |
Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells. |
format |
article |
author |
Aubin Michalon Andreas Hagenbuch Christian Huy Evita Varela Benoit Combaluzier Thibaud Damy Ole B. Suhr Maria J. Saraiva Christoph Hock Roger M. Nitsch Jan Grimm |
author_facet |
Aubin Michalon Andreas Hagenbuch Christian Huy Evita Varela Benoit Combaluzier Thibaud Damy Ole B. Suhr Maria J. Saraiva Christoph Hock Roger M. Nitsch Jan Grimm |
author_sort |
Aubin Michalon |
title |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
title_short |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
title_full |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
title_fullStr |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
title_full_unstemmed |
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
title_sort |
human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0bd15e092d1f47498ea907338e89a448 |
work_keys_str_mv |
AT aubinmichalon ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT andreashagenbuch ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT christianhuy ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT evitavarela ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT benoitcombaluzier ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT thibauddamy ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT olebsuhr ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT mariajsaraiva ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT christophhock ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT rogermnitsch ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT jangrimm ahumanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT aubinmichalon humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT andreashagenbuch humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT christianhuy humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT evitavarela humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT benoitcombaluzier humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT thibauddamy humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT olebsuhr humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT mariajsaraiva humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT christophhock humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT rogermnitsch humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells AT jangrimm humanantibodyselectivefortransthyretinamyloidremovescardiacamyloidthroughphagocyticimmunecells |
_version_ |
1718382900995424256 |