Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system

Abstract The GeneSwitch (GS) is a modified Gal4/UAS system, whereby transgene expression is induced in Drosophila by adding the drug RU486 to food. The GS system is routinely used in Drosophila aging and behavioral studies to avoid confounding effects related to genetic background mutations. Here, w...

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Bibliographic Details
Main Authors: Maricela Robles-Murguia, Liam C. Hunt, David Finkelstein, Yiping Fan, Fabio Demontis
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/0bdd8edebade4c678cefaaed563f6f11
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